Počet záznamů: 1

4-Deoxy-substrates for B-N-acetylhexosaminidases: How to make use of their loose specificity

  1. 1.
    0348173 - MBU-M 2011 RIV US eng J - Článek v odborném periodiku
    Slámová, Kristýna - Gažák, Radek - Bojarová, Pavla - Kulik, Natallia - Ettrich, Rüdiger - Pelantová, Helena - Sedmera, Petr - Křen, Vladimír
    4-Deoxy-substrates for B-N-acetylhexosaminidases: How to make use of their loose specificity.
    Glycobiology. Roč. 20, č. 8 (2010), s. 1002-1009 ISSN 0959-6658
    Grant CEP: GA ČR GP203/09/P024; GA ČR GD305/09/H008; GA MŠk(CZ) LC06010
    Výzkumný záměr: CEZ:AV0Z50200510; CEZ:AV0Z60870520
    Klíčová slova: beta-N-acetylhexosaminidase * 4-deoxy-glycoside * enzymatic synthesis
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 3.791, rok: 2010

    B-N-Acetylhexosaminidases feature so-called wobbling specificity, which means that Theky cleave substrates both in gluco- and galacto- configurations, with the activity ratio depending on the enzyme source. Here we present the new finding that fungal B-N-acetylhexosaminidases are able to hydrolyze and transfer 4-deoxy-N-acetylhexosaminides with high yields
    Trvalý link: http://hdl.handle.net/11104/0188770