Počet záznamů: 1

Modulation of type I iodothyronine 5’-deiodinase activity in white adipose tissue by nutrition: possible involvement of leptin

  1. 1.
    0347895 - FGU-C 2011 RIV CZ eng J - Článek v odborném periodiku
    Macek Jílková, Zuzana - Pavelka, Stanislav - Flachs, Pavel - Hensler, Michal - Kůs, Vladimír - Kopecký, Jan
    Modulation of type I iodothyronine 5’-deiodinase activity in white adipose tissue by nutrition: possible involvement of leptin.
    Physiological Research. Roč. 59, č. 4 (2010), s. 561-569 ISSN 0862-8408
    Grant CEP: GA ČR(CZ) GD305/08/H037; GA MŠk(CZ) OC08007
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: adipose tissue * thyroid hormones * obesity
    Kód oboru RIV: FB - Endokrinologie, diabetologie, metabolizmus, výživa
    Impakt faktor: 1.646, rok: 2010

    Our objective was to describe possible changes in activities of TH-metabolizing enzymes in white adipose tissue, and the role of TH metabolism in the tissue during obesogenic treatment, caloric restriction and in response to leptin in mice. Our results suggest a functional role for D1 in white adipose tissue, with D1 possibly being involved in the control of adipose tissue metabolism and/or accumulation of the tissue
    Trvalý link: http://hdl.handle.net/11104/0188565