Počet záznamů: 1

TGF-beta1 suppresses IL-6-induced STAT3 activation through regulation of Jak2 expression in prostate epithelial cells

  1. 1.
    0347188 - BFU-R 2011 RIV US eng J - Článek v odborném periodiku
    Staršíchová, Andrea - Lincová, Eva - Pernicová, Zuzana - Kozubík, Alois - Souček, Karel
    TGF-beta1 suppresses IL-6-induced STAT3 activation through regulation of Jak2 expression in prostate epithelial cells.
    Cellular Signalling. Roč. 22, č. 11 (2010), s. 1734-1744 ISSN 0898-6568
    Grant CEP: GA MZd NS9600
    Grant ostatní:GA ČR(CZ) GA310/07/0961
    Program:GA
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: interleukin-6 * transforming growth factor-beta * prostate
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 4.243, rok: 2010

    Our study demonstrated a novel interaction between TGF-beta1 and IL-6 signalling and suggested another mechanism of how defects in TGF-beta signalling, frequently associated with prostate pathologies, can contribute to the disruption of tissue homeostasis.
    Trvalý link: http://hdl.handle.net/11104/0188020