Počet záznamů: 1

The role of miRNAs and endogenous siRNAs in maternal-to-zygotic reprogramming and the establishment of pluripotency

  1. 1.
    0346834 - UMG-J 2011 RIV GB eng J - Článek v odborném periodiku
    Svoboda, Petr - Flemr, Matyáš
    The role of miRNAs and endogenous siRNAs in maternal-to-zygotic reprogramming and the establishment of pluripotency.
    Embo Reports. Roč. 11, č. 8 (2010), s. 590-597 ISSN 1469-221X
    Grant CEP: GA ČR GA204/09/0085; GA ČR GAP305/10/2215; GA MŠk ME09039
    Grant ostatní:EMBO SDIG(DE) project 1483
    Výzkumný záměr: CEZ:AV0Z50520514
    Klíčová slova: RNAi * miRNA * pluripotency
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 7.822, rok: 2010

    A review article discussing roles of RNA silencing in establishment and maintenance of pluripotency. A significant part of the transition of an oocyte into pluripotent cells of the embryo occurs in the absence of transcription. Therefore, post-transcriptional mechanisms (including RNA silencing) are important for proper reprogramming and establishment of pluripotency. The article is summarizing current data and is discussing possible roles of RNA silencing in establishment and maintenance of pluripotency.
    Trvalý link: http://hdl.handle.net/11104/0187753
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