Počet záznamů: 1
The role of miRNAs and endogenous siRNAs in maternal-to-zygotic reprogramming and the establishment of pluripotency
- 1.0346834 - ÚMG 2011 RIV GB eng J - Článek v odborném periodiku
Svoboda, Petr - Flemr, Matyáš
The role of miRNAs and endogenous siRNAs in maternal-to-zygotic reprogramming and the establishment of pluripotency.
Embo Reports. Roč. 11, č. 8 (2010), s. 590-597. ISSN 1469-221X. E-ISSN 1469-3178
Grant CEP: GA ČR GA204/09/0085; GA ČR GAP305/10/2215; GA MŠMT ME09039
Grant ostatní: EMBO SDIG(DE) project 1483
Výzkumný záměr: CEZ:AV0Z50520514
Klíčová slova: RNAi * miRNA * pluripotency
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 7.822, rok: 2010
A review article discussing roles of RNA silencing in establishment and maintenance of pluripotency. A significant part of the transition of an oocyte into pluripotent cells of the embryo occurs in the absence of transcription. Therefore, post-transcriptional mechanisms (including RNA silencing) are important for proper reprogramming and establishment of pluripotency. The article is summarizing current data and is discussing possible roles of RNA silencing in establishment and maintenance of pluripotency.
Trvalý link: http://hdl.handle.net/11104/0187753
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Počet záznamů: 1