0346356 - ÚOCHB 2011 RIV US eng J - Článek v odborném periodiku
Cahlíková, L. - Kulhánková, A. - Urbanová, Klára - Valterová, Irena - Macáková, K. - Kuneš, J.
Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-MS and Their Cholinesterase Activity.
Natural Product Communications. Roč. 5, č. 8 (2010), s. 1201-1204. ISSN 1934-578X. E-ISSN 1555-9475
Grant ostatní: GA UK(CZ) 122309
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: Zephyranthes robusta * Amaryllidaceae * GC/MS * acetylcholinesterase * butyrylcholinesterase
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 0.894, rok: 2010 ; AIS: 0.155, rok: 2010
Web výsledku:
www.naturalproduct.us

From the bulbs of Zephyranthes robusta Baker (Amaryllidaceae), seven known compounds, belonging to four structural types of Amaryllidaceae alkaloids, were identified and quantified by GC-MS. The alkaloid extract from the bulbs showed promising acetylcholinesterase and butyrylcholinesterase inhibitory activities against HuAChE (IC50 = 35.9 ± 3.5 μg/mL) and HuBuChE (IC50 = 190.9 ± 8.2 μg/mL).
Trvalý link: http://hdl.handle.net/11104/0187406