Počet záznamů: 1

Inhibition of canonical Wnt signaling promotes gliogenesis in PO-NSCs

  1. 1.
    0345341 - BFU-R 2011 RIV US eng J - Článek v odborném periodiku
    Kunke, D. - Bryja, Vítězslav - Mygland, L. - Arenas, E. - Krauss, S.
    Inhibition of canonical Wnt signaling promotes gliogenesis in PO-NSCs.
    Biochemical and Biophysical Research Communications. Roč. 386, č. 4 (2009), s. 628-633 ISSN 0006-291X
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: differentiation * gliogenesis * neuronal progenitor cells
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 2.548, rok: 2009

    Writ signaling plays an essential role in the development of mammalian central nervous system. We investigated the impact of activation/inhibition of the Writ signaling pathway on neuronal/glial differentiation in neurospheres derived from neonatal mouse forebrains. For short term alterations, neurospheres were stimulated with recombinant Wnt-3a, Wnt-5a and the Wnt inhibitor Dickkopf-1 (Dkk1).
    Trvalý link: http://hdl.handle.net/11104/0186637