Počet záznamů: 1

Growth/differentiation factor-15 inhibits differentiation into osteoclasts - A novel factor involved in control of osteoclast differentiation

  1. 1.
    0345304 - BFU-R 2011 RIV DE eng J - Článek v odborném periodiku
    Vaňhara, P. - Lincová, Eva - Kozubík, Alois - Jurdic, P. - Souček, Karel - Šmarda, J.
    Growth/differentiation factor-15 inhibits differentiation into osteoclasts - A novel factor involved in control of osteoclast differentiation.
    Differentiation. Roč. 78, č. 4 (2009), s. 213-222 ISSN 0301-4681
    Grant CEP: GA ČR(CZ) GA204/07/0834
    Grant ostatní: GA ČR(CZ) GA301/06/0036; GA ČR(CZ) GD204/08/H054; GA ČR(CZ) GA310/07/0961
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: osteoclast differentiation * GDF-15 * prostate cancer
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 3.311, rok: 2009

    Both purified GDF-15 and unpurified product secreted by prostate cancer cells strongly intereferes with differentiation of osteoclasts by inhibiting expression and activity of NFkappaB and c-Fos transcription factors.
    Trvalý link: http://hdl.handle.net/11104/0186612