Počet záznamů: 1

The reduction of doxorubicin at a mercury electrode and monitoring its interaction with DNA using constant current chronopotentiometry

  1. 1.
    0343810 - BFU-R 2011 RIV CZ eng J - Článek v odborném periodiku
    Vacek, J. - Havran, Luděk - Fojta, Miroslav
    The reduction of doxorubicin at a mercury electrode and monitoring its interaction with DNA using constant current chronopotentiometry.
    Collection of Czechoslovak Chemical Communications. Roč. 74, 11-12 (2009), s. 1727-1738 ISSN 0010-0765
    Grant CEP: GA ČR(CZ) GA203/07/1195; GA MŠk(CZ) LC06035; GA AV ČR(CZ) 1QS500040581
    Grant ostatní: GA AV ČR(CZ) IAA400040903
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: doxorubicin * mercury electrode * chronopotentiometry
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 0.856, rok: 2009

    Voltammetry with linear scan and chronopotentiometric stripping (CPS) with constant current were used for the analysis of doxorubicin (DOX) at the hanging mercury drop electrode. CPS was used for the study of DOX in situ electrochemical reduction in adsorbed state and for ex situ (adsorptive transfer) analysis of the drug. The CPS method was also applied to monitor the DOX interaction with double- and single-stranded DNA.
    Trvalý link: http://hdl.handle.net/11104/0186199