Počet záznamů: 1

Neural Stem/Progenitor Cells Derived from the Embryonic Dorsal Telencephalon of D6/GFP Mice Differentiate Primarily into Neurons After Transplantation into a Cortical Lesion

  1. 1.
    0343344 - UEM-P 2011 RIV US eng J - Článek v odborném periodiku
    Prajerová, Iva - Honsa, Pavel - Chvátal, Alexandr - Anděrová, Miroslava
    Neural Stem/Progenitor Cells Derived from the Embryonic Dorsal Telencephalon of D6/GFP Mice Differentiate Primarily into Neurons After Transplantation into a Cortical Lesion.
    Cellular and Molecular Neurobiology. Roč. 30, č. 2 (2010), s. 199-218 ISSN 0272-4340
    Grant CEP: GA ČR(CZ) GA305/09/0717; GA MŠk(CZ) LC554
    Grant ostatní:GA ČR(CZ) GD309/08/H079; GA MŠk(CZ) 1M0538; GA MŠk(CZ) GAUK62/2006/C/2
    Program:1M
    Výzkumný záměr: CEZ:AV0Z50390512
    Klíčová slova: ischemia * ion channels * injury and repair
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 2.423, rok: 2010

    D6 is a promoter/enhancer of the mDach1 gene that is involved in the development of the neocortex and hippocampus. Our results indicate that after transplantation into the site of a photochemical lesion, D6/GFP-derived NSPCs survive and differentiate into neurons, and their membrane properties are comparable to those transplanted into the non-injured cortex.
    Trvalý link: http://hdl.handle.net/11104/0185846