Počet záznamů: 1
Characterization of purinergic P2X4 receptor channels expressed in anterior pituitary cells
- 1.0343255 - FGÚ 2011 RIV US eng J - Článek v odborném periodiku
Zemková, Hana - Kučka, M. - Li, S. - Gonzales-Iglesias, A. E. - Tomic, M. - Stojilkovic, S. S.
Characterization of purinergic P2X4 receptor channels expressed in anterior pituitary cells.
American Journal of Physiology - Endocrinology And Metabolism. Roč. 298, č. 3 (2010), E664-E651. ISSN 0193-1849. E-ISSN 1522-1555
Grant CEP: GA MŠMT(CZ) LC554; GA ČR(CZ) GA305/07/0681
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: P2X4 receptor * ATP * pituitary
Kód oboru RIV: ED - Fyziologie
Impakt faktor: 4.686, rok: 2010
In rat anterior pituitary tissue, mRNA transcripts for the P2X4 subunit are the most abundant and the P2X4 protein is expressed. Extracellular ATP induces ivermectin-sensitive depolarizing current in a majority of thyrotropin-releasing hormone-responsive pituitary cells, and enhances prolactin release. These results indicate that lactotrophs express homomeric and/or heteromeric P2X4 receptors which facilitate hormone secretion
Trvalý link: http://hdl.handle.net/11104/0185773
Počet záznamů: 1