Počet záznamů: 1

Melatonin interactions with blood pressure and vascular function during l-NAME-induced hypertension

  1. 1.
    0343240 - FGU-C 2011 RIV DK eng J - Článek v odborném periodiku
    Paulis, L. - Pecháňová, Olga - Zicha, Josef - Barta, A. - Gardlik, R. - Celec, P. - Kuneš, Jaroslav - Šimko, F.
    Melatonin interactions with blood pressure and vascular function during l-NAME-induced hypertension.
    Journal of Pineal Research. Roč. 48, č. 2 (2010), s. 102-108 ISSN 0742-3098
    Grant CEP: GA AV ČR(CZ) IAA500110902
    Grant ostatní: VEGA(SK) 1/0187/09; VEGA(SK) 2/0178/09; APVV(SK) 0538-07; EC(XE) 2009-237834
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: endothelium-derived constricting factor * melatonin * nitric oxide
    Kód oboru RIV: FA - Kardiovaskulární nemoci vč. kardiochirurgie
    Impakt faktor: 5.855, rok: 2010

    To elucidate the possible role of the nitric oxide (NO) pathway in the hemodynamic actions of melatonin, the effects of this indolamine on vascular function during hypertension induced by NO-synthase (NOS) inhibition were investigated. It is evident that, in addition to the reduction of the oxidative load, the restoration of the NO pathway seems to play an important role in the antihypertensive effect of melatonin
    Trvalý link: http://hdl.handle.net/11104/0185759