Počet záznamů: 1

Use of rat genomics for investigating the metabolic syndrome

  1. 1.
    0341835 - FGU-C 2011 RIV US eng M - Část monografie knihy
    Pravenec, Michal
    Use of rat genomics for investigating the metabolic syndrome.
    Rat Genomics. New York: Humana Press, 2010 - (Anegom, I.), s. 415-426. ISBN 978-1-60327-388-6
    Grant CEP: GA MŠk(CZ) 1P05ME791; GA MŠk(CZ) 1M0520; GA ČR(CZ) GA301/06/0028; GA ČR(CZ) GA301/08/0166; GA AV ČR(CZ) IAA500110604
    Grant ostatní: EC(XE) LSHG-CT-2005-019015
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: spontaneously hypertensive rat * metabolic syndrome * genetics
    Kód oboru RIV: EB - Genetika a molekulární biologie

    The spontaneously hypertensive rat (SHR) is the most widely used animal model of essential hypertension and accompanying metabolic isturbances. In this model, the use of whole genome sequencing and gene expression profiling techniques, linkage and correlation analyses in recombinant inbred straíns, and in vitro and in vivo functional studies in congenic and transgenic lines has recently enabled molecular identification of quantitative trait loci relevant to the metabolic syndrome at the molecular level
    Trvalý link: http://hdl.handle.net/11104/0184699