Počet záznamů: 1

The effect of laparotomy on hydroxyl radicals, singlet oxygen and antioxidants measured by EPR method in the tails of rats

  1. 1.
    0340387 - UACH-T 2010 RIV SE eng J - Článek v odborném periodiku
    Fricová, J. - Stopka, Pavel - Křížová, Jana - Yamamotová, A. - Rokyta, R.
    The effect of laparotomy on hydroxyl radicals, singlet oxygen and antioxidants measured by EPR method in the tails of rats.
    Neuroendocrinology Letters. Roč. 30, č. 3 (2009), s. 373-376 ISSN 0172-780X
    Výzkumný záměr: CEZ:AV0Z40320502
    Klíčová slova: EPR-direct measurement in anesthetized rats * laparotomy * visceral pain
    Kód oboru RIV: ED - Fyziologie
    Impakt faktor: 1.047, rok: 2009

    The aim of the study was to demonstrate that direct measurement of hydroxyl radicals and singlet oxygen in the tail of living rats is possible. The basic level of hydroxyl radicals and singlet oxygen were measured and the effects of antioxidants on their levels were studied in the tail of living anaesthetized rats after acute postoperative pain. Laparotomy was performed as the source of acute abdominal pain. After closure of the abdominal cavity, the animals began to awaken within 30-60 minutes. They were left to recover for 2-3 hours; then they were reanesthetized and the effect of antioxidants was measured on the numbers of hydroxyl radicals and singlet oxygen via blood in the tail.
    Trvalý link: http://hdl.handle.net/11104/0183639