Počet záznamů: 1

Effect of maternal tobacco smoke exposure on the placental transcriptome

  1. 1.
    0340204 - UEM-P 2010 RIV GB eng J - Článek v odborném periodiku
    Bruchová, H. - Vašíková, A. - Merkerová, M. - Milcová, Alena - Topinka, Jan - Balaščak, I. - Pastorková, Anna - Šrám, Radim - Brdička, R.
    Effect of maternal tobacco smoke exposure on the placental transcriptome.
    Placenta. Roč. 31, č. 3 (2010), s. 186-191 ISSN 0143-4004
    Grant CEP: GA MŠk 2B06088
    Výzkumný záměr: CEZ:AV0Z50390512; CEZ:AV0Z50390703
    Klíčová slova: placenta * gene expression * tobacco smoke exposure
    Kód oboru RIV: DN - Vliv životního prostředí na zdraví
    Impakt faktor: 2.985, rok: 2010

    Gene expression profiling on placentas from women (N=12) and from women without significant exposure (N=64) were determined by Illumina HumanRef-8 v2 Expression BedChps with 18,216 gene probes. Microarray data were determined by moderated t-statistic. In smokers, deregulated genes were determined that show tissue non-specific induction and may be considered as general biomarkers of tobacco smoke exposure.
    Trvalý link: http://hdl.handle.net/11104/0196959