Počet záznamů: 1

A myeloperoxidase promoter polymorphism is independently associated with mortality in patients with impaired left ventricular function

  1. 1.
    0340135 - BFU-R 2010 RIV US eng J - Článek v odborném periodiku
    Rudolph, V. - Rudolph, T.K. - Kubala, Lukáš - Clauberg, N. - Maas, R. - Pekarová, Michaela - Klinke, A. - Lau, D. - Szöcs, K. - Meinertz, T. - Böger, R.H. - Baldus, S.
    A myeloperoxidase promoter polymorphism is independently associated with mortality in patients with impaired left ventricular function.
    Free Radical Biology and Medicine. Roč. 47, č. 11 (2009), s. 1584-1590 ISSN 0891-5849
    Grant CEP: GA ČR(CZ) GA524/08/1753
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: myeloperoxidase * heart failure * free radicals
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 6.081, rok: 2009

    Circulating levels of myeloperoxidase (MPO), a heme enzyme released upon activation of polymorphonuclear neutrophils, predict adverse outcome in patients with impaired left ventricular (LV) function. There is no association of the MPO polymorphism with total MPO protein concentration or MPO activity in plasma.
    Trvalý link: http://hdl.handle.net/11104/0183441