Počet záznamů: 1

Effect of polychlorinated biphenyls (PCBs) and 1,1,1-trichloro-2,2,-bis (4-chlorophenyl)-ethane (DDT) in follicular fluid on the results of in vitro fertilization-embryo transfer (IVF-ET) programs

  1. 1.
    0337397 - UIVT-O 2011 RIV US eng J - Článek v odborném periodiku
    Jirsová, S. - Mašata, J. - Jech, L. - Zvárová, Jana
    Effect of polychlorinated biphenyls (PCBs) and 1,1,1-trichloro-2,2,-bis (4-chlorophenyl)-ethane (DDT) in follicular fluid on the results of in vitro fertilization-embryo transfer (IVF-ET) programs.
    Fertility and Sterility. Roč. 93, č. 6 (2010), s. 1831-1836 ISSN 0015-0282
    Výzkumný záměr: CEZ:AV0Z10300504
    Klíčová slova: DDD * DDE * DDT * embryos * oocytes * PCB * pregnancy rate
    Kód oboru RIV: FK - Gynekologie a porodnictví
    Impakt faktor: 3.122, rok: 2010

    We analyzed the influence of polychlorinated biphenyls (PCBs) and pesticides in follicular fluid on the number of fertilized oocytes, the quality of oocytes and embryos, pregnancy rate, and number of embryos cryoconserved in IVF-ET program. We collected the follicular fluid of 99 infertile women. The PCB levels varied from 0.1 to 254.6 ng/g of fat. Levels of DDT and its metabolites varied from 0.3 to 35 228.8 ng/g of fat. A correlation was found between the number of diploid oocytes and the level of DDT, the fertilization of oocytes and level of PCB 158, and the pregnancy rate and the number of embryos cryoconserved and levels of PCB 47. Xenobiotics can be detected in the fat compartment of the follicular fluid. Some correlation to the IVF-ET program results was established, to a degree that might be considered of concern, although it was not statistically significant at the 5% level.
    Trvalý link: http://hdl.handle.net/11104/0181406