Počet záznamů: 1

Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter

  1. 1.
    0335970 - UEB-Q 2010 RIV GB eng J - Článek v odborném periodiku
    Mravec, J. - Skůpa, Petr - Bailly, A. - Hoyerová, Klára - Křeček, Pavel - Bielach, A. - Petrášek, Jan - Zhang, J. - Gaykova, V. - Stierhof, Y. D. - Dobrev, Petre - Schwarzerová, K. - Rolčík, Jakub - Seifertová, Daniela - Luschnig, Ch. - Benková, E. - Zažímalová, Eva - Geisler, M. - Friml, J.
    Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter.
    Nature. Roč. 459, č. 7250 (2009), s. 1136-1140 ISSN 0028-0836
    Grant CEP: GA AV ČR(CZ) IAA601630703; GA AV ČR KJB600380604; GA MŠk(CZ) LC06034
    Výzkumný záměr: CEZ:AV0Z50380511
    Klíčová slova: AtPIN5 * auxin efflux carrier * endoplasmic reticulum
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 34.480, rok: 2009

    Auxin is signalling molecule which mediates spatial and temporal coordination of plant growth and development via formation of ‘auxin gradients’. These gradients result from metabolic processes and the active directional transmembrane transport of auxin, which is catalyzed by auxin efflux carriers belonging to the PIN protein family. Investigation of atypical member of the family - AtPIN5 revealed its localization on the membranes of endoplasmic reticulum. The overexpression of the protein results in the striking change in the profile of auxin metabolites. These data show the so far unknown mechanism governing the availability of the key growth regulator in plant cells.
    Trvalý link: http://hdl.handle.net/11104/0180310