Počet záznamů: 1

Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. class III beta-tubulin

  1. 1.
    0334046 - UMG-J 2010 RIV US eng J - Článek v odborném periodiku
    Katsetos, C.D. - Dráberová, Eduarda - Legido, A. - Dumontet, C. - Dráber, Pavel
    Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. class III beta-tubulin.
    Journal of Cellular Physiology. Roč. 221, č. 3 (2009), s. 505-513 ISSN 0021-9541
    Grant CEP: GA AV ČR KAN200520701
    Výzkumný záměr: CEZ:AV0Z50520514
    Klíčová slova: Beta-II-tubulin * glioblastoma
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 4.586, rok: 2009

    This minireview focuses on microtubules and tubulin as emerging targets in potential therapy of GBM using a new class of betaIII-tubulin-targeted drugs in the light of recent developments concerning the function and potential role of this isotype in clinically aggressive tumor behavior, cancer stem cells, tumor hypoxia and chemoresistance to tubulin binding agents, principally taxanes.
    Trvalý link: http://hdl.handle.net/11104/0178881