Počet záznamů: 1

Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 6: 3D hydrogels with positive and negative surface charges and polyelectrolyte complexes in spinal cord injury repair

  1. 1.
    0332273 - UEM-P 2010 RIV GB eng J - Článek v odborném periodiku
    Hejčl, Aleš - Lesný, Petr - Přádný, Martin - Šedý, Jiří - Zámečník, J. - Jendelová, Pavla - Michálek, Jiří - Syková, Eva
    Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 6: 3D hydrogels with positive and negative surface charges and polyelectrolyte complexes in spinal cord injury repair.
    Journal of Materials Science-Materials in Medicine. Roč. 20, č. 7 (2009), s. 1571-1577 ISSN 0957-4530
    Grant CEP: GA AV ČR IAA500390902
    Grant ostatní: GA MŠk(CZ) 1M0538; GA MZd(CZ) 1A8697; EC FP6 project RESCUE(XE) LSHB-CT-2005-518233
    Výzkumný záměr: CEZ:AV0Z50390703; CEZ:AV0Z40500505
    Klíčová slova: transplantation * biomaterials * macroporous hydrogels
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 1.955, rok: 2009

    In this paper the authors evaluate 4 types of hydrogels based on 2-hydroxyethyl methacrylate, which differ in their surface charges. They find that hydrogels with surface charges improve cellular adhesion and axonal ingrowth compared to hydrogels with no surface charge. Further, hydrogels with positively charged surfaces improve the ingrowth of axons into the central parts of the bioimplants compared to hydrogels with negative charges.
    Trvalý link: http://hdl.handle.net/11104/0177582