Počet záznamů: 1

Thermoresponsive hydrolytically degradable polymer micelles intended for radionuclide delivery

  1. 1.
    0331564 - UMCH-V 2010 RIV DE eng J - Článek v odborném periodiku
    Hrubý, Martin - Koňák, Čestmír - Filippov, Sergey K. - Kučka, Jan - Větvička, David - Macková, Hana - Karlsson, G. - Edwards, K. - Říhová, Blanka - Ulbrich, Karel
    Thermoresponsive hydrolytically degradable polymer micelles intended for radionuclide delivery.
    Macromolecular Bioscience. Roč. 9, č. 10 (2009), s. 1016-1027 ISSN 1616-5187
    Grant CEP: GA AV ČR KAN200200651; GA ČR GA202/09/2078; GA ČR GD310/08/H077; GA MŠk 1M0505
    Výzkumný záměr: CEZ:AV0Z40500505; CEZ:AV0Z50200510; CEZ:AV0Z10480505
    Klíčová slova: block-copolymer micelles * drug-delivery * systems
    Kód oboru RIV: CD - Makromolekulární chemie
    Impakt faktor: 3.108, rok: 2009

    Novel polymer micelles, prepared by self-assembling thermoresponsive poly(N-isopropylacrylamide)-graft-poly[N-(2-hydroxypropyl)methacrylamide] copolymers with hydrolytically degradable N-glycosylamine groups between the polymer blocks were synthesized, characterized and proposed for delivery of diagnostic and therapeutic radionuclides into solid tumors.
    Trvalý link: http://hdl.handle.net/11104/0005520