Počet záznamů: 1

Resveratrol attenuates lipopolysaccharide-induced hepatitis in D-Galactosamine sensitized rats: Role of nitric oxide synthase 2 and heme oxygenase-1

  1. 1.
    0330496 - UEM-P 2010 RIV NL eng J - Článek v odborném periodiku
    Farghali, H. - Černý, D. - Kameníková, L. - Martínek, J. - Hořínek, A. - Kmoníčková, Eva - Zídek, Zdeněk
    Resveratrol attenuates lipopolysaccharide-induced hepatitis in D-Galactosamine sensitized rats: Role of nitric oxide synthase 2 and heme oxygenase-1.
    Nitric Oxide-Biology and Chemistry. Roč. 21, 3-4 (2009), s. 216-225 ISSN 1089-8603
    Grant CEP: GA ČR GA305/07/0061
    Grant ostatní: GA ČR(CZ) GA305/09/0004; GA MZd(CZ) NR9379
    Výzkumný záměr: CEZ:AV0Z50390512
    Klíčová slova: resveratrol * lipopolysacchride * nitrix oxide
    Kód oboru RIV: FR - Farmakologie a lékárnická chemie
    Impakt faktor: 2.506, rok: 2009

    Resveratrol improves hepatotoxic markers and morphology after the hepatic insult. Among the mechanisms responsible for the hepatoprotective effects of resveratrol are reduction of NO production, downeregulation of nitric oxide synthese, madification of oxidative stress parameters and modulation of heme oxygenase-1.
    Trvalý link: http://hdl.handle.net/11104/0176277