Počet záznamů: 1

Reduced susceptibility to ischemia-induced arrhythmias in the preconditioned rat heart is independent of PI3-kinase/Akt

  1. 1.
    0328562 - FGU-C 2010 RIV CZ eng J - Článek v odborném periodiku
    Ravingerová, T. - Matejíková, J. - Pancza, D. - Kolář, František
    Reduced susceptibility to ischemia-induced arrhythmias in the preconditioned rat heart is independent of PI3-kinase/Akt.
    Physiological Research. Roč. 58, č. 3 (2009), s. 443-447 ISSN 0862-8408
    Grant CEP: GA ČR(CZ) GA305/07/0875; GA MŠk MEB080837
    Grant ostatní: VEGA(SK) 2/0173/08; APVV(SK) SK-CZ-0049-07
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: myocardial ischemia * PI3-kinase/Akt * arrhythmias
    Kód oboru RIV: FA - Kardiovaskulární nemoci vč. kardiochirurgie
    Impakt faktor: 1.430, rok: 2009

    PI3K/Akt inhibition by wortmannin did not affect reduced arrhythmogenesis during ischemia in preconditioned rat hearts indicating that, in contrast to its positive role in the irreversible myocardial injury, PI3K/Akt activity is not required for protection induced by preconditioning against ischemic arrhythmias
    Trvalý link: http://hdl.handle.net/11104/0174853