Počet záznamů: 1

Hyphenated ultra high-performance liquid chromatography–Nano Quantity

  1. 1.
    0327080 - MBU-M 2010 RIV NL eng J - Článek v odborném periodiku
    Olšovská, Jana - Kameník, Zdeněk - Cajthaml, Tomáš
    Hyphenated ultra high-performance liquid chromatography–Nano Quantity.
    Journal of Chromatography A. Roč. 1216, č. 30 (2009), s. 5774-5778 ISSN 0021-9673
    Grant CEP: GA MŠk 1M06011
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: macrolides * uv detection * ultra high-perfonmance liquid chromatography
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 4.101, rok: 2009

    A novel universal aerosol-based detector Nano Quantity Analyte Detector – NQADTM, connected with an ultra-performance liquid chromatography system is described. The detector was employed for detection of selected antibiotic compounds – macrolides (oleandomycin, erythromycin, troleandomycin, clarithromycin and roxithromycin) that are hard to detect using classical UV detectors due to the lack of chromophores. The determined lowest detection limits under isocratic conditions for these compounds ranged from 3.0 to 5.4 μg/mL. The suitability of the detector connected with ultra high-performance liquid chromatography in the gradient mode was tested on a more complex mixture containing 12 antibiotics. The detector exhibited full compatibility under both the elution modes when UHPLC separations were achieved in relatively short run times
    Trvalý link: http://hdl.handle.net/11104/0173980