Výsledky vyhledávání
- 1.0564278 - ÚOCHB 2023 FR eng A - Abstrakt
Šnajdr, Ivan - Krečmerová, Marcela - Bell, B. - Alt, J. - Gori, S. - Rais, R. - Majer, Pavel - Slusher, B.
Synthesis and biological activity of itaconate prodrugs.
EFMC-ISMC 2022. 27th International Symposium on Medicinal Chemistry. Nice: Société de Chimie Thérapeutique, 2022, č. článku 146..
[EFMC-ISMC 2022. International Symposium on Medicinal Chemistry /27./. 04.09.2022-08.09.2022, Nice]
Institucionální podpora: RVO:61388963
Klíčová slova: itaconates * prodrugs * inflammation
Obor OECD: Medicinal chemistry
Trvalý link: https://hdl.handle.net/11104/0335987 - 2.0545193 - ÚOCHB 2022 US eng A - Abstrakt
Lemberg, K. M. - Aguilar, J. M. H. - Alt, J. - Krečmerová, Marcela - Majer, Pavel - Rais, R. - Slusher, B.
A novel protide purine antimetabolite combines with the prodrug glutamine antagonist JHU395 in preclinical models of Ras-driven sarcomas.
Cancer Research. American Association for Cancer Research. Roč. 81, č. 13 (2021). ISSN 0008-5472. E-ISSN 1538-7445.
[AACR Annual Meeting 2021. 10.04.2021-15.04.2021, online]
Institucionální podpora: RVO:61388963
Obor OECD: Organic chemistry
https://doi.org/10.1158/1538-7445.AM2021-1293
Trvalý link: http://hdl.handle.net/11104/0321931 - 3.0521281 - ÚOCHB 2020 US eng A - Abstrakt
Tenora, Lukáš - Novotná, Kateřina - Jančařík, Andrej - Rais, R. - Alt, J. - Slusher, B. S. - Majer, Pavel
Prodrugs of 6-Diazo-5-oxo-L-norleucine: Strategy for Delivery in Brain and Potencial Treatment of Lymphoma.
Boulder Peptide Symposium 2019. Boulder: Boulder Peptide Society, 2019.
[Boulder Peptide Symposium 2019. 23.09.2019-26.09.2019, Boulder]
Institucionální podpora: RVO:61388963
Klíčová slova: prodrugs * 6-diazo-5-oxo-L-norleucine * brain targeting
Obor OECD: Medicinal chemistry
Trvalý link: http://hdl.handle.net/11104/0305914 - 4.0521273 - ÚOCHB 2020 GR eng A - Abstrakt
Tenora, Lukáš - Novotná, Kateřina - Jančařík, Andrej - Rais, R. - Alt, J. - Slusher, B. S. - Majer, Pavel
Prodrugs of 6-Diazo-5-oxo-L-norleucine: Strategy for Delivery in Brain and Potencial Treatment of Lymphoma.
EFMC-ASMC’19. 8th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry. Athens: European Federation for Medicinal Chemistry, 2019. s. 294.
[EFMC-ASMC’19. EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry /8./. 01.09.2019-05.09.2019, Athens]
Institucionální podpora: RVO:61388963
Klíčová slova: prodrugs * 6-diazo-5-oxo-L-norleucine * brain targeting
Obor OECD: Medicinal chemistry
Trvalý link: http://hdl.handle.net/11104/0305911 - 5.0521256 - ÚOCHB 2020 US eng A - Abstrakt
Šnajdr, Ivan - Jančařík, Andrej - Tenora, Lukáš - Nedelcovych, M. - Alt, J. - Englert, J. - Rojas, C. - Le, A. - Elgogary, A. - Tan, J. - Monincová, Lenka - Pate, K. - Adams, R. - Ferraris, D. - Powell, J. - Majer, Pavel - Rais, R. - Slusher, B. S.
Prodrugs of 6-Diazo-5-oxo-L-norleucine (DON) with Enhanced CSF Delivery in Monkeys as a Potential Treatment for Glioblastoma.
Boulder Peptide Symposium 2019. Boulder: Boulder Peptide Society, 2019.
[Boulder Peptide Symposium 2019. 23.09.2019-26.09.2019, Boulder]
Institucionální podpora: RVO:61388963
Klíčová slova: DON * glioblastoma * prodrugs
Obor OECD: Medicinal chemistry
Trvalý link: http://hdl.handle.net/11104/0305888 - 6.0521237 - ÚOCHB 2020 GR eng A - Abstrakt
Šnajdr, Ivan - Jančařík, Andrej - Tenora, Lukáš - Nedelcovych, M. - Alt, J. - Englert, J. - Rojas, C. - Le, A. - Elgogary, A. - Tan, J. - Monincová, Lenka - Pate, K. - Adams, R. - Ferraris, D. - Powell, J. - Majer, Pavel - Rais, R. - Slusher, B. S.
Prodrugs of 6-Diazo-5-oxo-L-norleucine (DON) with Enhanced CSF Delivery in Monkeys as a Potential Treatment for Glioblastoma.
EFMC-ASMC’19. 8th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry. Athens: European Federation for Medicinal Chemistry, 2019. s. 352.
[EFMC-ASMC’19. EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry /8./. 01.09.2019-05.09.2019, Athens]
Institucionální podpora: RVO:61388963
Klíčová slova: DON * glioblastoma * prodrugs
Obor OECD: Medicinal chemistry
Trvalý link: http://hdl.handle.net/11104/0305872 - 7.0500743 - ÚOCHB 2019 IL eng A - Abstrakt
Rais, R. - Jančařík, Andrej - Tenora, Lukáš - Šnajdr, Ivan - Nedelcovych, M. - Alt, J. - Englert, J. - Rojas, C. - Le, A. - Elgogary, A. - Tan, J. - Monincová, Lenka - Pate, K. - Adams, R. - Ferraris, D. - Powell, J. - Majer, Pavel - Slusher, B. S.
Discovery of 6-Diazo-5-oxo-L-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma.
Joint Prague-Weizmann Winter School on Drug Discovery 2018. Rehovot: Weizmann Institute of Science, 2018.
[Joint Prague-Weizmann Winter School on Drug Discovery 2018. 03.12.2018-07.12.2018, Rehovot]
Institucionální podpora: RVO:61388963
Klíčová slova: 6-diazo-5-oxo-L-norleucine * glioblastoma
Obor OECD: Medicinal chemistry
Trvalý link: http://hdl.handle.net/11104/0292775 - 8.0500719 - ÚOCHB 2019 CZ eng A - Abstrakt
Rais, R. - Jančařík, Andrej - Tenora, Lukáš - Šnajdr, Ivan - Nedelcovych, M. - Alt, J. - Englert, J. - Rojas, C. - Le, A. - Elgogary, A. - Tan, J. - Monincová, Lenka - Pate, K. - Adams, R. - Ferraris, D. - Powell, J. - Majer, Pavel - Slusher, B. S.
Discovery of 6-Diazo-5-oxo-L-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma.
Liblice 2018. 53rd Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2018. s. 128.
[Liblice 2018. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /53./. 02.11.2018-04.11.2018, Lázně Bělohrad]
Institucionální podpora: RVO:61388963
Klíčová slova: 6-diazo-5-oxo-L-norleucine * glioblastoma
Obor OECD: Medicinal chemistry
Trvalý link: http://hdl.handle.net/11104/0292760 - 9.0485402 - ÚOCHB 2018 CZ eng A - Abstrakt
Tenora, Lukáš - Novotná, Kateřina - Jančařík, Andrej - Monincová, Lenka - Gadiano, A. J. - Dash, R. - Rais, R. - Alt, J. - Slusher, B. S. - Majer, Pavel
Design and Synthesis of Brain-Targeted Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo-L-norleucine.
Liblice 2017. 52nd Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2017. s. 119.
[Liblice 2017. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /52./. 03.11.2017-05.11.2017, Lázně Bělohrad]
Institucionální podpora: RVO:61388963
Klíčová slova: DON * glutamine antagonist * prodrugs
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0280604 - 10.0485374 - ÚOCHB 2018 CZ eng A - Abstrakt
Tenora, Lukáš - Novotná, Kateřina - Jančařík, Andrej - Rais, R. - Alt, J. - Slusher, B. S. - Majer, Pavel
Design and Synthesis of Cell-Targeted Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo-L-norleucine.
Liblice 2017. 52nd Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2017. s. 103.
[Liblice 2017. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /52./. 03.11.2017-05.11.2017, Lázně Bělohrad]
Institucionální podpora: RVO:61388963
Klíčová slova: glutamine antagonist * DON * produgs
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0280583