Výsledky vyhledávání
- 1.0490992 - BC 2019 RIV GB eng J - Článek v odborném periodiku
Assumpção, T.C. - Mizurini, D.M. - Ma, D. - Monteiro, R.Q. - Ahlstedt, S. - Reyes, M. - Kotsyfakis, Michalis - Mather, T. N. - Andersen, J. F. - Lukszo, J. - Ribeiro, J.M.C. - Francischetti, I.M.B.
Ixonnexin from Tick Saliva Promotes Fibrinolysis by Interacting with Plasminogen and Tissue-Type Plasminogen Activator, and Prevents Arterial Thrombosis.
Scientific Reports. Roč. 8, 19 March (2018), č. článku 4806. ISSN 2045-2322. E-ISSN 2045-2322
Grant CEP: GA ČR GAP502/12/2409
Institucionální podpora: RVO:60077344
Klíčová slova: factor pathway inhibitor * heparin-binding exosite * ixodes-scapularis * borrelia-burgdorferi * factor-xa * hematophagous animals * platelet-aggregation * potent inhibitor
Obor OECD: Genetics and heredity (medical genetics to be 3)
Impakt faktor: 4.011, rok: 2018
https://www.nature.com/articles/s41598-018-22780-1
Trvalý link: http://hdl.handle.net/11104/0285092 - 2.0461181 - BC 2017 RIV US eng J - Článek v odborném periodiku
Assumpção, T.C. - Ma, D. - Mizurini, D.M. - Kini, D.M. - Ribeiro, J.M.C. - Kotsyfakis, Michalis - Monteiro, R.Q. - Francischetti, I.M.B.
In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus.
PLoS Neglected Tropical Diseases. Roč. 10, č. 1 (2016), č. článku e0004298. ISSN 1935-2735. E-ISSN 1935-2735
Institucionální podpora: RVO:60077344
Klíčová slova: thrombin inhibitor * salivary gland * anticolagulant protein
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 3.834, rok: 2016
Trvalý link: http://hdl.handle.net/11104/0261400 - 3.0451374 - BC 2016 RIV US eng J - Článek v odborném periodiku
Jablonka, W. - Kotsyfakis, Michalis - Mizurini, D.M. - Monteiro, R.Q. - Lukszo, J. - Drake, S.K. - Ribeiro, J.M.C. - Andersen, J. F.
Identification and Mechanistic Analysis of a Novel Tick-Derived Inhibitor of Thrombin.
PLoS ONE. Roč. 10, č. 8 (2015), e0133991. ISSN 1932-6203. E-ISSN 1932-6203
Grant CEP: GA ČR GAP502/12/2409
Institucionální podpora: RVO:60077344
Klíčová slova: Haemaphysalis longicornis * binding inhibitor * crystal structure
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 3.057, rok: 2015
Trvalý link: http://hdl.handle.net/11104/0252562 - 4.0435190 - BC 2015 RIV US eng J - Článek v odborném periodiku
Waisberg, M. - Molina-Cruz, A. - Mizurini, D.M. - Gera, N. - Sousa, B.C. - Ma, D. - Leal, A.C. - Gomes, T. - Kotsyfakis, Michalis - Ribeiro, J.M.C. - Lukszo, J. - Reiter, K. - Porcella, S.F. - Oliveira, C. J. - Monteiro, R.Q. - Barillas-Mury, C. - Pierce, S.K. - Francischetti, I.M.B.
Plasmodium falciparum Infection Induces Expression of a Mosquito Salivary Protein (Agaphelin) That Targets Neutrophil Function and Inhibits Thrombosis without Impairing Hemostasis.
PLoS Pathogens. Roč. 10, č. 9 (2014), e1004338. ISSN 1553-7366. E-ISSN 1553-7374
Grant CEP: GA ČR GAP502/12/2409
Institucionální podpora: RVO:60077344
Klíčová slova: factor pathway inhibitor * platelet aggregation * in vivo * serine proteases * arterial thrombosis * gene expression * structure prediction
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 7.562, rok: 2014
Trvalý link: http://hdl.handle.net/11104/0239107 - 5.0423812 - BC 2014 RIV DE eng J - Článek v odborném periodiku
Ma, C. - Mizurini, D.M. - Assumpção, T.C.F. - Li, Y. - Qi, Y. - Kotsyfakis, Michalis - Ribeiro, J.M.C. - Monteiro, R.Q. - Francischetti, I.M.B.
Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo.
Thrombosis and Haemostasis. Roč. 122, č. 25 (2013), s. 4094-4106. ISSN 0340-6245. E-ISSN 2567-689X
Grant CEP: GA ČR GAP502/12/2409
Institucionální podpora: RVO:60077344
Klíčová slova: Desmolaris * anticolagulant * vampire bat saliva * FXIa
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 5.760, rok: 2013
Trvalý link: http://hdl.handle.net/11104/0229880 - 6.0380194 - BC 2013 RIV US eng J - Článek v odborném periodiku
Collin, N. - Assumpção, T.C.F. - Mizurini, D.M. - Gilmore, D. - Dutra-Oliveira, A. - Kotsyfakis, Michalis - Sa-Nunes, A. - Teixeira, C. - Ribeiro, J.M.C. - Monteiro, R.Q. - Valenzuela, J. G. - Francischetti, I.M.B.
Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly lutzomyia longipalpis, blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo.
Arteriosclerosis Thrombosis and Vascular Biology. Roč. 32, č. 9 (2012), s. 2185-2198. ISSN 1079-5642. E-ISSN 1524-4636
Grant CEP: GA ČR GAP502/12/2409
Institucionální podpora: RVO:60077344
Klíčová slova: hematophagy * leishmaniasis * microcirculation * thrombosis * vector biology
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 6.338, rok: 2012
http://atvb.ahajournals.org/content/32/9/2185
Trvalý link: http://hdl.handle.net/11104/0210967 - 7.0375991 - BC 2013 RIV US eng J - Článek v odborném periodiku
Francischetti, I.M.B. - Oliveira, C. J. - Ostera, G. R. - Yager, S. B. - Debierre-Grockiego, F. - Carregaro, V. - Jaramillo-Gutierrez, G. - Hume, J. C. C. - Jiang, L. - Moretz, S. E. - Lin, Ch. K. - Ribeiro, J.M.C. - Long, C. A. - Vickers, B. K. - Schwarz, R. T. - Seydel, K. B. - Iacobelli, M. - Ackerman, H. C. - Srinivasan, P. - Gomes, R. B. - Wang, X. - Monteiro, R.Q. - Kotsyfakis, Michalis - Sa-Nunes, A. - Waisberg, M.
Defibrotide Interferes With Several Steps of the Coagulation-Inflammation Cycle and Exhibits Therapeutic Potential to Treat Severe Malaria.
Arteriosclerosis Thrombosis and Vascular Biology. Roč. 32, č. 3 (2012), s. 786-798. ISSN 1079-5642. E-ISSN 1524-4636
Výzkumný záměr: CEZ:AV0Z60220518
Klíčová slova: anticoagulants * blood coagulation * endothelium * microcirculation * vascular biology * malaria * defibrotide * inflammation
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 6.338, rok: 2012
Trvalý link: http://hdl.handle.net/11104/0208512 - 8.0364839 - BC 2012 RIV US eng J - Článek v odborném periodiku
Calvo, E. - Mizurini, D.M. - Sa-Nunes, A. - Ribeiro, J.M.C. - Andersen, J. F. - Mans, B.J. - Monteiro, R.Q. - Kotsyfakis, Michalis - Francischetti, I.M.B.
Alboserpin, a Factor Xa Inhibitor from the Mosquito Vector of Yellow Fever, Binds Heparin and Membrane Phospholipids and Exhibits Antithrombotic Activity.
Journal of Biological Chemistry. Roč. 286, č. 32 (2011), 27998-28010. ISSN 0021-9258. E-ISSN 1083-351X
Výzkumný záměr: CEZ:AV0Z60220518
Klíčová slova: serpin * mosquito * Aedes albopictus * phospholipids * Factor Xa * heparin * binding affinity * coagulation * thrombus * bleeding
Kód oboru RIV: GJ - Choroby a škůdci zvířat, veterinární medicína
Impakt faktor: 4.773, rok: 2011
Trvalý link: http://hdl.handle.net/11104/0200216