Výsledky vyhledávání
- 1.0564278 - ÚOCHB 2023 FR eng A - Abstrakt
Šnajdr, Ivan - Krečmerová, Marcela - Bell, B. - Alt, J. - Gori, S. - Rais, R. - Majer, Pavel - Slusher, B.
Synthesis and biological activity of itaconate prodrugs.
EFMC-ISMC 2022. 27th International Symposium on Medicinal Chemistry. Nice: Société de Chimie Thérapeutique, 2022, č. článku 146..
[EFMC-ISMC 2022. International Symposium on Medicinal Chemistry /27./. 04.09.2022-08.09.2022, Nice]
Institucionální podpora: RVO:61388963
Klíčová slova: itaconates * prodrugs * inflammation
Obor OECD: Medicinal chemistry
Trvalý link: https://hdl.handle.net/11104/0335987 - 2.0557262 - ÚOCHB 2023 NL eng A - Abstrakt
Peters, D. - Norris, L. - Tenora, Lukáš - Šnajdr, Ivan - Zhu, X. - Sakamoto, S. - Veeravalli, V. - Thomas, A. - Majer, Pavel - Rais, R. - Slusher, B.
Discovery of IBD3540: A Novel Gut-Restricted Glutamate Carboxypeptidase II Inhibitor with Preclinical Anti-Colitis Activity.
Journal of Crohns & Colitis. Oxford University Press. Roč. 16 (2022), I174-I175. ISSN 1873-9946. E-ISSN 1876-4479.
[Congress of ECCO /17./. 16.02.2022-19.02.2022, online]
Institucionální podpora: RVO:61388963
Klíčová slova: glutamate carboxypeptidase
Obor OECD: Biochemistry and molecular biology
https://doi.org/10.1093/ecco-jcc/jjab232.197
Trvalý link: http://hdl.handle.net/11104/0331342 - 3.0545193 - ÚOCHB 2022 US eng A - Abstrakt
Lemberg, K. M. - Aguilar, J. M. H. - Alt, J. - Krečmerová, Marcela - Majer, Pavel - Rais, R. - Slusher, B.
A novel protide purine antimetabolite combines with the prodrug glutamine antagonist JHU395 in preclinical models of Ras-driven sarcomas.
Cancer Research. American Association for Cancer Research. Roč. 81, č. 13 (2021). ISSN 0008-5472. E-ISSN 1538-7445.
[AACR Annual Meeting 2021. 10.04.2021-15.04.2021, online]
Institucionální podpora: RVO:61388963
Obor OECD: Organic chemistry
https://doi.org/10.1158/1538-7445.AM2021-1293
Trvalý link: http://hdl.handle.net/11104/0321931 - 4.0480720 - ÚOCHB 2018 GB eng A - Abstrakt
Tichý, Tomáš - Rais, R. - Vávra, Jan - Tenora, Lukáš - Monincová, Lenka - Dash, R. - Slusher, B. - Majer, Pavel
Orally bioavailable prodrugs of a hydroxamate-based glutamate carboxypeptidase II inhibitor.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 344. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963
Klíčová slova: glutamate carboxypeptidase II inhibitor * prodrugs
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276428 - 5.0472510 - ÚOCHB 2017 US eng A - Abstrakt
Nedelcovych, M. - Kim, B. H. - Rais, R. - Jančařík, Andrej - Tenora, Lukáš - Alt, J. - Kelschenbach, J. - Majer, Pavel - Volsky, D. - Slusher, B.
Brain delivery of the glutamine antagonist 6-Diazo-5-oxo-L-norleucine (DON) via prodrug approach: a potential treatment for HIV-associated neurocognitive disorders (HAND).
Journal of Neurovirology. Roč. 22, Suppl 1 (2016), S57-S58. ISSN 1355-0284. E-ISSN 1538-2443.
[International Symposium on NeuroVirology /14./. 25.10.2016-28.10.2016, Toronto]
Institucionální podpora: RVO:61388963
Klíčová slova: glutamate * DON * HAND treatment
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0269849