Výsledky vyhledávání
- 1.0564278 - ÚOCHB 2023 FR eng A - Abstrakt
Šnajdr, Ivan - Krečmerová, Marcela - Bell, B. - Alt, J. - Gori, S. - Rais, R. - Majer, Pavel - Slusher, B.
Synthesis and biological activity of itaconate prodrugs.
EFMC-ISMC 2022. 27th International Symposium on Medicinal Chemistry. Nice: Société de Chimie Thérapeutique, 2022, č. článku 146..
[EFMC-ISMC 2022. International Symposium on Medicinal Chemistry /27./. 04.09.2022-08.09.2022, Nice]
Institucionální podpora: RVO:61388963
Klíčová slova: itaconates * prodrugs * inflammation
Obor OECD: Medicinal chemistry
Trvalý link: https://hdl.handle.net/11104/0335987 - 2.0545193 - ÚOCHB 2022 US eng A - Abstrakt
Lemberg, K. M. - Aguilar, J. M. H. - Alt, J. - Krečmerová, Marcela - Majer, Pavel - Rais, R. - Slusher, B.
A novel protide purine antimetabolite combines with the prodrug glutamine antagonist JHU395 in preclinical models of Ras-driven sarcomas.
Cancer Research. American Association for Cancer Research. Roč. 81, č. 13 (2021). ISSN 0008-5472. E-ISSN 1538-7445.
[AACR Annual Meeting 2021. 10.04.2021-15.04.2021, online]
Institucionální podpora: RVO:61388963
Obor OECD: Organic chemistry
https://doi.org/10.1158/1538-7445.AM2021-1293
Trvalý link: http://hdl.handle.net/11104/0321931 - 3.0468507 - ÚOCHB 2017 US eng A - Abstrakt
Krečmerová, Marcela - Tichý, Tomáš - Pomeisl, Karel - Andrei, G. - Balzarini, J. - Snoeck, R.
Antiviral acyclic nucleoside phosphonates: New structures and prodrugs.
Madridge Journal of Pharmaceutical Research. Roč. 1, č. 2 (2016), s. 37
[PharmaMed-2016. International Conference on Medicinal and Pharmaceutical Chemistry. 05.12.2016-07.12.2016, Dubai]
Grant CEP: GA ČR(CZ) GA14-00522S
Institucionální podpora: RVO:61388963
Klíčová slova: acyclic nucleoside phosphonates * prodrugs * antivirals * 5-azacytosine
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0266341 - 4.0468476 - ÚOCHB 2017 US eng A - Abstrakt
Agrawal, K. - Das, V. - Otmar, Miroslav - Krečmerová, Marcela - Džubák, P. - Hajdúch, M.
Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D and xenograft models.
Molecular Cancer Therapeutics. American Association for Cancer Research. Roč. 14, Suppl 2 (2015), B72. ISSN 1535-7163. E-ISSN 1538-8514.
[AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics. 05.11.2015-09.11.2015, Boston]
Grant CEP: GA MPO(CZ) FR-TI4/625; GA MŠMT(CZ) LO1304
Institucionální podpora: RVO:61388963
Klíčová slova: demethylation * epigenetic drugs * fluorescence detection system
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0266318 - 5.0459451 - ÚOCHB 2017 US eng A - Abstrakt
Agrawal, K. - Vojta, P. - Holub, D. - Frydrych, I. - Džubák, P. - Otmar, Miroslav - Krečmerová, Marcela - Hajdúch, M.
5-azacytidine nucleosides and their derivatives: Molecular hallmarks of drug resistance & alternative therapeutic regimen.
Cancer Research. American Association for Cancer Research. Roč. 75, 15 Suppl (2015), s. 2944. ISSN 0008-5472. E-ISSN 1538-7445.
[Annual Meeting of the American Association for Cancer Research (AACR) /106./. 18.04.2015-22.04.2015, Philadelphia]
Grant CEP: GA MPO(CZ) FR-TI4/625
Institucionální podpora: RVO:61388963
Klíčová slova: drug resistance * 5-azacytidine * 2'-deoxy-5-azacytidine
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0259641 - 6.0455024 - ÚOCHB 2016 IL eng A - Abstrakt
Krečmerová, Marcela
Trends and challenges in chemistry of acyclic nucleoside phosphonates.
6th International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC'15) and 13th Annual Meeting of the Medicinal Chemistry Section of the Israel Chemical Society. Rehovot: European Federation for Medicinal Chemistry, 2015. s. 164.
[International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC'15) /6./ and Annual Meeting of the Medicinal Chemistry Section of the Israel Chemical Society /13./. 15.11.2015-18.11.2015, Rehovot]
Grant CEP: GA MPO(CZ) FR-TI4/625
Institucionální podpora: RVO:61388963
Klíčová slova: 5-azacytosine * PME-azaC * acyclic nucleoside phosphonate * antivirals * prodrug
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0255679 - 7.0454334 - ÚOCHB 2016 CZ eng A - Abstrakt
Lamatová, Nikola - Krečmerová, Marcela - Spiwok, V. - Brabcová, Jana
Enzymatic synthesis of ester prodrugs of acyclic nucleoside analogues by Candida antarctica lipase.
Liblice 2015. 50th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2015. s. 106.
[Liblice 2015. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /50./. 06.11.2015-08.11.2015, Olomouc]
Grant CEP: GA ČR(CZ) GA14-00522S
Institucionální podpora: RVO:61388963
Klíčová slova: vinil esters * lipase * enzymatic esterification
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0256245 - 8.0444391 - ÚOCHB 2016 US eng A - Abstrakt
Agrawal, K. - Džubák, P. - Frydrych, I. - Holub, D. - Vojta, P. - Krečmerová, Marcela - Otmar, Miroslav - Hajdúch, M.
5-azacytidine nucleosides and their derivatives: Molecular hallmarks of drug resistance.
Cancer Research. American Association for Cancer Research. Roč. 74, č. 19 Suppl (2014), s. 400. ISSN 0008-5472. E-ISSN 1538-7445.
[Annual Meeting of the American Association for Cancer Research (AACR) /105./. 05.04.2014-09.04.2014, San Diego]
Grant CEP: GA MPO(CZ) FR-TI4/625
Grant ostatní: OP VaVpI(CZ) CZ.1.05/2.1.00/01.0030
Institucionální podpora: RVO:61388963
Klíčová slova: drug resistance * 5-azacytidine * 2'-deoxy-5-azacytidine
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0247102 - 9.0436686 - ÚOCHB 2015 PT eng A - Abstrakt
Tichý, Tomáš - Pomeisl, Karel - Williams, M. - Krylov, I. - McKenna, C. - Krečmerová, Marcela
Tyrosine-based prodrugs of acyclic nucleoside phosphonates.
EFMC-ISMC 2014. 23rd International Symposium on Medicinal Chemistry. Lisbon: -, 2014.
[EFMC-ISMC 2014. International Symposium on Medicinal Chemistry /23./. 07.09.2014-11.09.2014, Lisbon]
Grant CEP: GA ČR(CZ) GA14-00522S
Grant ostatní: GA AV ČR(CZ) M200551201
Institucionální podpora: RVO:61388963
Klíčová slova: prodrugs * phosphonates * tyrosine
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0240428 - 10.0436535 - ÚOCHB 2015 CZ eng A - Abstrakt
Šolínová, Veronika - Kaiser, Martin Maxmilian - Lukáč, Miloš - Janeba, Zlatko - Krečmerová, Marcela - Holý, Antonín - Kašička, Václav
Chiral analysis of antiviral acyclic nucleoside phosphonates-based drugs and their analogs by capillary electrophoresis.
ISSS 2014. 20th International Symposium on Separation Sciences. Pardubice: Univerzita Pardubice, 2014 - (Horna, A.; Jandera, P.). s. 104. ISBN 978-80-7395-777-3.
[ISSS 2014. International Symposium on Separation Sciences /20./. 30.08.2014-02.09.2014, Praha]
Grant CEP: GA ČR(CZ) GAP206/12/0453; GA ČR(CZ) GA13-17224S; GA MV VG20102015046
Institucionální podpora: RVO:61388963
Klíčová slova: acyclic nucleoside phosphonates * capillary electrophoresis * chiral analysis
Kód oboru RIV: CB - Analytická chemie, separace
Trvalý link: http://hdl.handle.net/11104/0240419