Výsledky vyhledávání
- 1.0480770 - ÚOCHB 2018 GB eng A - Abstrakt
Eisenreichová, Andrea - Humpolíčková, Jana - Bouřa, Evžen
Genetically encoded fluorescent probe to visualize phosphatidylinositol.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 364-365. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Grant CEP: GA ČR GJ15-21030Y; GA MŠMT LO1302
Institucionální podpora: RVO:61388963
Klíčová slova: phosphatidylinositol * fluorescent probe
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276466 - 2.0480769 - ÚOCHB 2018 GB eng A - Abstrakt
Vorlová, Barbora - Kašpárek, Petr - Šácha, Pavel - Sedláček, Radislav - Konvalinka, Jan
Revealing novel functions of glutamate carboxypeptidase II using knock-out mice.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 358. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963 ; RVO:68378050
Klíčová slova: glutamate carboxypeptidase II * knock-out mice
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276464 - 3.0480761 - ÚOCHB 2018 GB eng A - Abstrakt
Tenora, Lukáš - Novotná, Kateřina - Monincová, Lenka - Jančařík, Andrej - Gadiano, A. J. - Dash, R. - Rais, R. - Alt, J. - Slusher, B. S. - Majer, Pavel
Design and synthesis of brain-targeted prodrugs of the glutamine antagonist 6-Diazo-5-oxo-L-norleucine.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 345. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963
Klíčová slova: 6-Diazo-5-oxo-L-norleucine * prodrugs
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276459 - 4.0480746 - ÚOCHB 2018 GB eng A - Abstrakt
Tenora, Lukáš - Novotná, Kateřina - Monincová, Lenka - Jančařík, Andrej - Nedelcovych, M. - Alt, J. - Rais, R. - Slusher, B. S. - Majer, Pavel
Design and synthesis of brain-targeted prodrugs of the glutamine antagonist 6-Diazo-5-oxo-L-norleucine.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 344. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963
Klíčová slova: 6-Diazo-5-oxo-L-norleucine * prodrugs
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276451 - 5.0480720 - ÚOCHB 2018 GB eng A - Abstrakt
Tichý, Tomáš - Rais, R. - Vávra, Jan - Tenora, Lukáš - Monincová, Lenka - Dash, R. - Slusher, B. - Majer, Pavel
Orally bioavailable prodrugs of a hydroxamate-based glutamate carboxypeptidase II inhibitor.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 344. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963
Klíčová slova: glutamate carboxypeptidase II inhibitor * prodrugs
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276428 - 6.0480718 - ÚOCHB 2018 GB eng A - Abstrakt
Šácha, Pavel - Dvořáková, Petra - Knedlík, Tomáš - Schimer, Jiří - Šubr, Vladimír - Ulbrich, Karel - Bušek, P. - Navrátil, Václav - Sedlák, František - Majer, Pavel - Šedo, A. - Konvalinka, Jan
iBodies: modular synthetic antibody mimetics based on hydrophilic polymers decorated with functional moieties as tools for molecular recognition, imaging and specific drug delivery.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 340. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963 ; RVO:61389013
Klíčová slova: antibody mimetics * molecular recognition * polymer conjugates
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276426 - 7.0480717 - ÚOCHB 2018 GB eng A - Abstrakt
Tichá, Anežka - Stanchev, Stancho - Vinothkumar, K. - Mikles, David C. - Pachl, Petr - Švehlová, Kateřina - Nguyen, M. - Verhelst, S. - Johnson, D. - Bachovchin, D. - Majer, Pavel - Stříšovský, Kvido
A modular and generalizable route to potent, selective and pharmacologically compliant inhibitors of rhomboid proteases.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 335. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963
Klíčová slova: rhomboid proteases * inhibitors
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276423 - 8.0480714 - ÚOCHB 2018 GB eng A - Abstrakt
Mejdrová, Ivana - Humpolíčková, Jana - Nencka, Radim - Bouřa, Evžen
Rational design of novel highly potent and selective phosphatidylinositol 4-kinase III-beta (PI4KB) inhibitors as broad-spectrum antiviral agents and tools for chemical biology.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 333. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Grant CEP: GA ČR GJ15-21030Y; GA MŠMT LO1302
Institucionální podpora: RVO:61388963
Klíčová slova: PI4KB * antivirals
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276421 - 9.0480712 - ÚOCHB 2018 GB eng A - Abstrakt
Hánová, Iva - Brynda, Jiří - Hobizalová, Radka - Alam, N. - Sojka, Daniel - Kopáček, Petr - Marešová, Lucie - Vondrášek, Jiří - Horn, Martin - Schueler-Furman, O. - Mareš, Michael
Novel structural mechanism of allosteric regulation of aspartic peptidases via evolutionary conserved exosite.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 300-301. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963 ; RVO:60077344
Klíčová slova: aspartic peptidases * exosite inhibition
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276419 - 10.0480709 - ÚOCHB 2018 GB eng A - Abstrakt
Srp, Jaroslav - Pachl, Petr - Mishra, Manasi - Horn, Martin - Mareš, Michael
A novel non-canonical binding mode for serine proteases on plant Kunitz inhibitors.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 299. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963
Klíčová slova: Kunitz inhibitors * serine proteases
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276416