Výsledky vyhledávání
- 1.0583119 - BC 2024 RIV US eng A - Abstrakt
Kunzová, Michaela - Doleželová, Eva - Zíková, Alena
Dysregulation of mitochondrial bioenergetics leads to elevated ROS levels and promotes programmed developmental progression of Trypanosoma brucei.
European Journal of Clinical Investigation. Wiley. Roč. 53, č. 1 (2023), č. článku 57ASM – 161. ISSN 0014-2972. E-ISSN 1365-2362.
[57TH ANNUAL SCIENTIFIC MEETING-7-9 June 2023, Prague, Czech Republic. 07.06.2023-09.06.2023, Praha]
GRANT EU: European Commission(XE) 101044951 - MitoSignal
Institucionální podpora: RVO:60077344
Klíčová slova: bioenergetics * mitochondrial * Trypanosoma brucei
Obor OECD: Microbiology
https://onlinelibrary.wiley.com/doi/10.1111/eci.13992
Trvalý link: https://hdl.handle.net/11104/0351112 - 2.0576571 - BC 2024 RIV US eng A - Abstrakt
Doleželová, Eva - Kunzová, Michaela - Panicucci, Brian - Zíková, Alena
Trypanosoma brucei, a master of metabolic disguise.
European Journal of Clinical Investigation. Wiley. Roč. 53, č. 1 (2023), č. článku 57ASM - 24. ISSN 0014-2972. E-ISSN 1365-2362.
[57TH ANNUAL SCIENTIFIC MEETING-7-9 June 2023, Prague, Czech Republic. 07.06.2023-09.06.2023, Praha]
GRANT EU: European Commission(XE) 101044951 - MitoSignal
Institucionální podpora: RVO:60077344
Klíčová slova: Dysregulation * mitochondrial * Trypanosoma brucei
Obor OECD: Microbiology
https://onlinelibrary.wiley.com/doi/10.1111/eci.13992
Trvalý link: https://hdl.handle.net/11104/0351107 - 3.0561826 - BC 2023 RIV NL eng A - Abstrakt
Gahura, Ondřej - Muhleip, A. - Hierro Yap, Carolina - Panicucci, Brian - Jain, Minal - Hollaus, D. - Slapničková, Martina - Zíková, Alena - Amunts, A.
Mitochondrial ATP synthase of trypanosomes reveals the mechanism of oligomerization and its evolution.
Biochimica Et Biophysica Acta-Bioenergetics. Elsevier. Roč. 1863 (2022), s. 10-10, č. článku 148628. ISSN 0005-2728. E-ISSN 1879-2650
Institucionální podpora: RVO:60077344
Klíčová slova: Mitochondrial * ATP * trypanosomes
Obor OECD: Biochemistry and molecular biology
https://www.sciencedirect.com/science/article/pii/S0005272822000986
Trvalý link: https://hdl.handle.net/11104/0339046 - 4.0518502 - ÚOCHB 2020 CZ eng A - Abstrakt
Hocková, Dana - Doleželová, Eva - Terán, D. - Špaček, Petr - Česnek, Michal - Gahura, Ondřej - Kotrbová, Zuzana - Keough, D. T. - Zíková, Alena - Guddat, L. W.
Acyclic nucleoside phosphonates as inhibitors of Trypanosoma brucei 6-oxopurine phosphoribosyltransferases.
Liblice 2019. 54th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2019. s. 89.
[Liblice 2019. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /54./. 06.11.2019-08.11.2019, Špindlerův Mlýn]
Grant CEP: GA ČR(CZ) GA16-06049S; GA MŠMT(CZ) LL1205
Institucionální podpora: RVO:61388963 ; RVO:60077344
Klíčová slova: nucleotide analogues * enzyme inhibitors * HG(X)PRT
Obor OECD: Organic chemistry
Trvalý link: http://hdl.handle.net/11104/0303896 - 5.0518497 - ÚOCHB 2020 TH eng A - Abstrakt
Hocková, Dana - Zíková, Alena - Keough, D. T. - Guddat, L. W.
Modular synthesis of N-branched acyclic nucleoside phosphonates (aza-ANPs) designed as inhibitors of 6-oxopurine phosphoribosyltransferases.
20th Tetrahedron Symposium. Bangkok: Elsevier, 2019. P1.104, „P1014“.
[Tetrahedron Symposium /20./. 18.06.2019-21.06.2019, Bangkok]
Institucionální podpora: RVO:61388963 ; RVO:60077344
Klíčová slova: nucleotide analogues * enzyme inhibitors * HG(X)PRT
Obor OECD: Organic chemistry
Trvalý link: http://hdl.handle.net/11104/0303883 - 6.0500128 - ÚOCHB 2019 JP eng A - Abstrakt
Hocková, Dana - Zíková, Alena - Keough, D. T. - Guddat, L. W.
Modular Synthesis of N-Branched Acyclic Nucleoside Phosphonates (aza-ANPs) Designed as Inhibitors of 6-Oxopurine Phosphoribosyltransferases.
IKCOC-14. 14th International Kyoto Conference on New Aspects of Organic Chemistry. Kyoto: Kyoto University, 2018. s. 80.
[IKCOC-14. International Kyoto Conference on New Aspects of Organic Chemistry /14./. 12.11.2018-16.11.2018, Kyoto]
Grant CEP: GA ČR(CZ) GA16-06049S
Institucionální podpora: RVO:61388963 ; RVO:60077344
Klíčová slova: nucleotide analogues * enzyme inhibitors * HG(X)PRT
Obor OECD: Organic chemistry
Trvalý link: http://hdl.handle.net/11104/0292312 - 7.0485092 - ÚOCHB 2018 CN eng A - Abstrakt
Hocková, Dana - Keough, D. T. - Špaček, Petr - Terán, D. - Zíková, Alena - Eng, W. S. - Janeba, Zlatko - Naesens, L. - Chavchich, M. - West, N. P. - Edstein, M. - Guddat, L. W.
Acyclic nucleoside phosphonates (ANPs): Inhibition and structural investigations of 6-oxopurine phosphoribosyltranferases as drug targets.
IDDST 2017. BIT's 15th Annual Congress of International Drug Discovery Science and Technology. Xi'an: BIT, 2017. s. 146.
[IDDST 2017. BIT’s Annual Congress of International Drug Discovery Science and Technology /15./. 09.11.2017-11.11.2017, Xi'an]
Grant CEP: GA ČR(CZ) GA16-06049S; GA MŠMT LL1205
Institucionální podpora: RVO:61388963 ; RVO:60077344
Klíčová slova: enzyme inhibitors * HGPRT * purine salvage pathvay * antiparasitic * prodrugs
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0280304 - 8.0481205 - ÚOCHB 2018 CZ eng A - Abstrakt
Hocková, Dana - Zíková, Alena - Terán, D. - Špaček, Petr - Naesens, L. - Janeba, Zlatko - Keough, D. T. - Guddat, L. W.
Acyclic nucleoside phosphonates: Inhibition and structural investigations of Trypanosoma brucei 6-oxopurine phosphoribosyltranferases.
SCNAC 2017. 17th Symposium on Chemistry of Nucleic Acid Components. Praha: Confis Conference, 2017. s. 148.
[SCNAC 2017. Symposium on Chemistry of Nucleic Acid Components /17./. 04.06.2017-09.06.2017, Český Krumlov]
Grant CEP: GA ČR(CZ) GA16-06049S; GA MŠMT LL1205
Institucionální podpora: RVO:61388963 ; RVO:60077344
Klíčová slova: nucleotide analogues * enzyme inhibitors * Trypanosoma brucei
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0276805