Výsledky vyhledávání
- 1.0454968 - ÚEB 2016 RIV GB eng J - Journal Article
Řezníčková, Eva - Weitensteiner, S. - Havlíček, Libor - Jorda, Radek - Gucký, Tomáš - Berka, K. - Bazgier, Václav - Zahler, S. - Kryštof, Vladimír - Strnad, Miroslav
Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro.
Chemical Biology & Drug Design. Roč. 86, č. 6 (2015), s. 1528-1540. ISSN 1747-0277. E-ISSN 1747-0285
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA14-19590S; GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : angiogenesis * apoptosis * aurora A
Subject RIV: CE - Biochemistry
Impact factor: 2.802, year: 2015
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord&UT=000367376800022
Permanent Link: http://hdl.handle.net/11104/0255626File Download Size Commentary Version Access 2015_Reznickova_CHEMICAL BIOLOGY & DRUG DESIGN_1528.pdf 1 2.2 MB Other open-access - 2.0454915 - ÚEB 2016 RIV GB eng J - Journal Article
Jorda, Radek - Schütznerová, E. - Cankař, P. - Brychtová, Veronika - Navrátilová, Jana - Kryštof, Vladimír
Novel arylazopyrazole inhibitors of cyclin-dependent kinases.
Bioorganic & Medicinal Chemistry. Roč. 23, č. 9 (2015), s. 1975-1981. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA14-19590S; GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : Cyclin-dependent kinases * Inhibitor * Cell cycle
Subject RIV: CE - Biochemistry
Impact factor: 2.923, year: 2015
Permanent Link: http://hdl.handle.net/11104/0255588File Download Size Commentary Version Access 2015_Jorda_BIOORGANIC & MEDICINAL CHEMISTRY_1975.pdf 3 1.3 MB Other open-access - 3.0446805 - ÚEB 2016 RIV US eng J - Journal Article
Havlíček, Libor - Moravcová, Daniela - Kryštof, Vladimír - Strnad, Miroslav
The Identification of a Novel Highly Condensed Pentacyclic Heteroaromatic Ring System 1,3,5,5b,6,8,10,10b-Octaazacyclopenta[h,i]Aceanthrylene and its Application in the Synthesis of 5,7-Substituted Pyrazolo[4,3-d]Pyrimidines.
Journal of Heterocyclic Chemistry. Roč. 52, č. 3 (2015), s. 669-673. ISSN 0022-152X. E-ISSN 1943-5193
R&D Projects: GA ČR GAP305/12/0783
Institutional support: RVO:61389030
Keywords : roscovitine * pyrazolo[4,3-d]pyrimidine * kinase inhibitor
Subject RIV: CE - Biochemistry
Impact factor: 0.685, year: 2015
Permanent Link: http://hdl.handle.net/11104/0248761File Download Size Commentary Version Access 2015_Havlicek_JOURNAL OF HETEROCYCLIC CHEMISTRY_669.pdf 2 307.5 KB Author’s postprint open-access - 4.0446637 - ÚEB 2016 RIV GB eng J - Journal Article
Mojzych, M. - Karczmarzyk, Z. - Wysocki, W. - Ceruso, M. - Supuran, C.T. - Kryštof, Vladimír - Urbanczyk-Lipkowska, Z. - Kalicki, P.
New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity.
Bioorganic & Medicinal Chemistry. Roč. 23, č. 7 (2015), s. 1421-1429. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA ČR GAP305/12/0783
Grant - others:GA MŠk(CZ) ED0007/01/01
Program: ED
Institutional support: RVO:61389030
Keywords : Sildenafil analogues * Pyrazolo[4,3-e][1,2,4] triazine * Sulfonamides
Subject RIV: CE - Biochemistry
Impact factor: 2.923, year: 2015
Permanent Link: http://hdl.handle.net/11104/0248606File Download Size Commentary Version Access 2015_Mojzych_BIOORGANIC & MEDICINAL CHEMISTRY_1421.pdf 0 1.2 MB Other open-access - 5.0433741 - ÚEB 2015 RIV GB eng J - Journal Article
Jorda, Radek - Navrátilová, Jana - Hušková, Zlata - Schütznerová, E. - Cankař, P. - Strnad, Miroslav - Kryštof, Vladimír
Arylazopyrazole AAP1742 Inhibits CDKs and Induces Apoptosis in Multiple Myeloma Cells via Mcl-1 Downregulation.
Chemical Biology & Drug Design. Roč. 84, č. 4 (2014), s. 402-408. ISSN 1747-0277. E-ISSN 1747-0285
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA14-19590S; GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : CAN508 * cyclin-dependent kinase * inhibitor
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.485, year: 2014
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=MEDLINE&DestLinkType=FullRecord&UT=24803299
Permanent Link: http://hdl.handle.net/11104/0237916File Download Size Commentary Version Access 2014_Jorda_CHEMICAL BIOLOGY & DRUG DESIGN_402.pdf 1 801.1 KB Other open-access - 6.0423094 - ÚEB 2014 RIV FR eng J - Journal Article
Imramovský, A. - Jorda, Radek - Pauk, K. - Řezníčková, Eva - Dušek, J. - Hanousek, J. - Kryštof, Vladimír
Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines.
European Journal of Medicinal Chemistry. Roč. 68, č. 2013 (2013), s. 253-259. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA301/08/1649
Institutional research plan: CEZ:AV0Z50380511
Keywords : Diamides * Apoptosis * Cytotoxicity
Subject RIV: CE - Biochemistry
Impact factor: 3.432, year: 2013
Permanent Link: http://hdl.handle.net/11104/0229347File Download Size Commentary Version Access 2013_Imramovsky_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_253.pdf 0 729.5 KB Other open-access - 7.0421049 - ÚEB 2014 RIV US eng J - Journal Article
Haider, C. - Grubinger, M. - Řezníčková, Eva - Weiss, T.S. - Rotheneder, H. - Miklos, W. - Berger, W. - Jorda, Radek - Zatloukal, M. - Gucký, T. - Strnad, Miroslav - Kryštof, Vladimír - Mikulits, W.
Novel Inhibitors of Cyclin-Dependent Kinases Combat Hepatocellular Carcinoma without Inducing Chemoresistance.
Molecular Cancer Therapeutics. Roč. 12, č. 10 (2013), s. 1947-1957. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA301/08/1649
Institutional research plan: CEZ:AV0Z50380511
Keywords : PRIMARY HUMAN HEPATOCYTES * SELICICLIB R-ROSCOVITINE * CELL-CYCLE
Subject RIV: CE - Biochemistry
Impact factor: 6.107, year: 2013
Permanent Link: http://hdl.handle.net/11104/0227508File Download Size Commentary Version Access 2013_Haider_MOLECULAR CANCER THERAPEUTICS_1947-1957.pdf 11 1.6 MB Other open-access - 8.0399222 - ÚEB 2014 RIV US eng J - Journal Article
Gucký, T. - Jorda, Radek - Zatloukal, M. - Bazgier, V. - Berka, K. - Řezníčková, Eva - Béres, T. - Strnad, Miroslav - Kryštof, Vladimír
A Novel Series of Highly Potent 2,6,9-Trisubstituted Purine Cyclin-Dependent Kinase Inhibitors.
Journal of Medicinal Chemistry. Roč. 56, č. 15 (2013), s. 6234-6247. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GAP305/12/0783; GA ČR GD203/09/H046
Grant - others:GA MŠk(CZ) ED0007/01/01; GA MŠk(CZ) ED2.1.00/03.0058; GA MŠk(CZ) EE2.3.20.0017
Program: ED; ED; EE
Institutional research plan: CEZ:AV0Z50380511
Keywords : CHRONIC LYMPHOCYTIC-LEUKEMIA * DINACICLIB SCH 727965 * CELL-CYCLE
Subject RIV: ED - Physiology
Impact factor: 5.480, year: 2013
Permanent Link: http://hdl.handle.net/11104/0226634File Download Size Commentary Version Access 2013_Gucky_JOURNAL OF MEDICINAL CHEMISTRY_6234.pdf 0 1.2 MB Other open-access - 9.0396979 - ÚEB 2014 RIV FR eng J - Journal Article
Dolečková, Iva - Česnek, Michal - Dračínský, Martin - Brynda, Jiří - Voller, J. - Janeba, Zlatko - Kryštof, Vladimír
Synthesis and biological evaluation of guanidino analogues of roscovitine.
European Journal of Medicinal Chemistry. Roč. 62, April 2013 (2013), s. 443-452. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT 1M0508; GA ČR GAP305/12/0783
Grant - others:GA MŠk(CZ) ED0007/01/01
Program: ED
Institutional research plan: CEZ:AV0Z50380511; CEZ:AV0Z40550506
Keywords : 6-Guanidinopurine * Olomoucine * Roscovitine
Subject RIV: CE - Biochemistry
Impact factor: 3.432, year: 2013
Permanent Link: http://hdl.handle.net/11104/0224681File Download Size Commentary Version Access 2013_Doleckova_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_443.pdf 0 494.8 KB Other open-access - 10.0395483 - ÚEB 2014 RIV FR eng J - Journal Article
Zatloukal, M. - Jorda, Radek - Gucký, T. - Řezníčková, Eva - Voller, Jiří - Pospíšil, T. - Malínková, V. - Adamcová, H. - Kryštof, Vladimír - Strnad, Miroslav
Synthesis and in vitro biological evaluation of 2,6,9-trisubstituted purines targeting multiple cyclin-dependent kinases.
European Journal of Medicinal Chemistry. Roč. 61, SI (2013), s. 61-72. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA301/08/1649
Grant - others:GA MŠk(CZ) ED0007/01/01
Program: ED
Institutional research plan: CEZ:AV0Z50380511
Keywords : Cyclin-dependent kinase * Inhibitor * Roscovitine
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.432, year: 2013
Permanent Link: http://hdl.handle.net/11104/0223515File Download Size Commentary Version Access 2013_Zatloukal_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_61.pdf 6 662.5 KB Other open-access