Výsledky vyhledávání
- 1.0485324 - ÚOCHB 2018 CZ eng A - Abstrakt
Bařinková, Jitka - Vávra, Jan - Tichý, Tomáš - Rais, R. - Tenora, Lukáš - Dash, R. - Monincová, Lenka - Slusher, B. S. - Majer, Pavel
Orally Bioavailable Prodrugs of a Hydroxamate-Based Glutamate Carboxypeptidase II Inhibitor.
Liblice 2017. 52nd Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2017. s. 47.
[Liblice 2017. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /52./. 03.11.2017-05.11.2017, Lázně Bělohrad]
Institucionální podpora: RVO:61388963
Klíčová slova: GCPII inhibition * neuropathy treatment * oral bioavailability
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0280542 - 2.0480720 - ÚOCHB 2018 GB eng A - Abstrakt
Tichý, Tomáš - Rais, R. - Vávra, Jan - Tenora, Lukáš - Monincová, Lenka - Dash, R. - Slusher, B. - Majer, Pavel
Orally bioavailable prodrugs of a hydroxamate-based glutamate carboxypeptidase II inhibitor.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 344. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963
Klíčová slova: glutamate carboxypeptidase II inhibitor * prodrugs
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276428 - 3.0468507 - ÚOCHB 2017 US eng A - Abstrakt
Krečmerová, Marcela - Tichý, Tomáš - Pomeisl, Karel - Andrei, G. - Balzarini, J. - Snoeck, R.
Antiviral acyclic nucleoside phosphonates: New structures and prodrugs.
Madridge Journal of Pharmaceutical Research. Roč. 1, č. 2 (2016), s. 37
[PharmaMed-2016. International Conference on Medicinal and Pharmaceutical Chemistry. 05.12.2016-07.12.2016, Dubai]
Grant CEP: GA ČR(CZ) GA14-00522S
Institucionální podpora: RVO:61388963
Klíčová slova: acyclic nucleoside phosphonates * prodrugs * antivirals * 5-azacytosine
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0266341 - 4.0436686 - ÚOCHB 2015 PT eng A - Abstrakt
Tichý, Tomáš - Pomeisl, Karel - Williams, M. - Krylov, I. - McKenna, C. - Krečmerová, Marcela
Tyrosine-based prodrugs of acyclic nucleoside phosphonates.
EFMC-ISMC 2014. 23rd International Symposium on Medicinal Chemistry. Lisbon: -, 2014.
[EFMC-ISMC 2014. International Symposium on Medicinal Chemistry /23./. 07.09.2014-11.09.2014, Lisbon]
Grant CEP: GA ČR(CZ) GA14-00522S
Grant ostatní: GA AV ČR(CZ) M200551201
Institucionální podpora: RVO:61388963
Klíčová slova: prodrugs * phosphonates * tyrosine
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0240428 - 5.0422695 - ÚOCHB 2014 FR eng A - Abstrakt
Špaček, Petr - Keough, D. T. - Hocková, Dana - Tichý, Tomáš - Vrbková, Silvie - Slavětínská, Lenka - Janeba, Zlatko - Naesens, L. - Edstein, M. D. - Chavchich, M. - Wang, T. - de Jersey, J. - Guddat, L. W.
Acyclic nucleoside phosphonates containing a second phosphonate group as potent inhibitors of 6-oxopurine phosphoribosyltransferases with antimalarial activity.
ESOC 2013. 18th European Symposium on Organic Chemistry. Marseille: -, 2013. s. 183-183.
[ESOC 2013. European Symposium on Organic Chemistry /18./. 07.07.2013-12.07.2013, Marseille]
Grant CEP: GA ČR GAP207/11/0108
Institucionální podpora: RVO:61388963
Klíčová slova: nucleotide analogues * enzyme inhibitors * Plasmodium
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0228958 - 6.0399428 - ÚOCHB 2014 CZ cze A - Abstrakt
Krečmerová, Marcela - Tichý, Tomáš - Pomeisl, Karel
Nové formy proléčiv biologicky aktivních nukleotidových analogů.
[New prodrug forms of biologically active nucleotide analogues.]
Liblice 2013. 48th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2013. s. 33-33.
[Liblice 2013. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /48./. 01.11.2013-03.11.2013, Špindlerův Mlýn]
Grant CEP: GA MPO FR-TI4/625
Institucionální podpora: RVO:61388963
Klíčová slova: acyclic nucleoside phosphonate * antivirals * cytostatics * prodrug
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0226713 - 7.0399050 - ÚOCHB 2014 US eng A - Abstrakt
Tichý, Tomáš - Andrei, G. - Snoeck, R. - Balzarini, J. - Dračínský, Martin - Krečmerová, Marcela
Synthesis and Antiviral Activities of Hexadecyloxypropyl Prodrugs of Acyclic Nucleoside Phosphonates Containing Guanine or Hypoxanthine and a (S)-HPMP or PEE Acyclic Moiety.
26th International Conference on Antiviral Research (ICAR). San Francisco: International Society for Antiviral Research (ISAR), 2013. s. 108-108.
[International Conference on Antiviral Research /26./. 11.05.2013-15.05.2013, San Francisco]
Grant ostatní: AV ČR(CZ) M200551201
Institucionální podpora: RVO:61388963
Klíčová slova: acyclic nucleoside phosphonate * antivirals * prodrug
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0226445 - 8.0399039 - ÚOCHB 2014 US eng A - Abstrakt
Williams, M. M. - Kashemirov, B. A. - Krečmerová, Marcela - Tichý, Tomáš - Prichard, M. N. - Drach, J. C. - Hilfinger, J. M. - McKenna, Ch. E.
Novel 2,4-diaminopyrimidine Nucleoside Phosphonate Antiviral Prodrugs.
26th International Conference on Antiviral Research (ICAR). San Francisco: International Society for Antiviral Research (ISAR), 2013. s. 81-82.
[International Conference on Antiviral Research /26./. 11.05.2013-15.05.2013, San Francisco]
Grant CEP: GA MŠMT(CZ) ME10040
Grant ostatní: AV ČR(CZ) M200551201
Institucionální podpora: RVO:61388963
Klíčová slova: acyclic nucleoside phosphonate * antivirals * tyrosine
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0226442 - 9.0384395 - ÚOCHB 2013 US eng A - Abstrakt
Tichý, Tomáš - Andrei, G. - Snoeck, R. - Balzarini, J. - Dračínský, Martin - Krečmerová, Marcela
Synthesis and antiviral activities of hexadecyloxypropyl produgs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety.
2nd Antivirals Congress. From Bench to Bedside. Cambridge: Elsevier, 2012.
[Antivirals Congress. From Bench to Bedside /2./. 11.11.2012-13.11.2012, Cambridge]
Institucionální podpora: RVO:61388963
Klíčová slova: acyclic nucleoside phosphonate * prodrugs * antiviral * herpes virus * hexadecyloxypropyl
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0214066 - 10.0384386 - ÚOCHB 2013 US eng A - Abstrakt
Krečmerová, Marcela - Blažek, Jiří - Tichý, Tomáš - Andrei, G. - Balzarini, J. - Snoeck, R.
New Approaches in Development of Prodrugs of Antivirally Active Acyclic Nucleoside Phosphonates.
2nd Antivirals Congress. From Bench to Bedside. Cambridge: Elsevier, 2012.
[Antivirals Congress. From Bench to Bedside /2./. 11.11.2012-13.11.2012, Cambridge]
Grant CEP: GA MŠMT(CZ) ME10040
Institucionální podpora: RVO:61388963
Klíčová slova: acyclic nucleoside phosphonate * prodrug * amidate * POM
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0214060