Výsledky vyhledávání
- 1.0422695 - ÚOCHB 2014 FR eng A - Abstrakt
Špaček, Petr - Keough, D. T. - Hocková, Dana - Tichý, Tomáš - Vrbková, Silvie - Slavětínská, Lenka - Janeba, Zlatko - Naesens, L. - Edstein, M. D. - Chavchich, M. - Wang, T. - de Jersey, J. - Guddat, L. W.
Acyclic nucleoside phosphonates containing a second phosphonate group as potent inhibitors of 6-oxopurine phosphoribosyltransferases with antimalarial activity.
ESOC 2013. 18th European Symposium on Organic Chemistry. Marseille: -, 2013. s. 183-183.
[ESOC 2013. European Symposium on Organic Chemistry /18./. 07.07.2013-12.07.2013, Marseille]
Grant CEP: GA ČR GAP207/11/0108
Institucionální podpora: RVO:61388963
Klíčová slova: nucleotide analogues * enzyme inhibitors * Plasmodium
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0228958 - 2.0399947 - ÚOCHB 2014 eng A - Abstrakt
Hocková, Dana - Keough, D. T. - Janeba, Zlatko - Naesens, L. - Edstein, M. D. - Chavchich, M. - Wang, T. H. - de Jersey, J. - Guddat, L. W.
New Anti-malarial Drug Leads: N-Branched Acyclic Nucleoside Phosphonates as Inhibitors of the Plasmodium falciparum and vivax 6-Oxopurine Phosphoribosyltransferases.
44th World Chemistry Congress. Istanbul: IUPAC, 2013. s. 1629-1629.
[World Chemistry Congress /44./. 11.08.2013-16.08.2013, Istanbul]
Grant CEP: GA ČR GAP207/11/0108
Grant ostatní: NHMRC(AU) 1030353
Institucionální podpora: RVO:61388963
Klíčová slova: nucleotide analogues * enzyme inhibitors * Plasmodium
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0227125 - 3.0399866 - ÚOCHB 2014 JP eng A - Abstrakt
Hocková, Dana - Keough, D. T. - Špaček, Petr - Janeba, Zlatko - Naesens, L. - Edstein, M. D. - Chavchich, M. - Wang, T. H. - de Jersey, J. - Guddat, L. W.
Acyclic nucleoside bisphosphonates as inhibitors of 6-oxopurine phosphoribosyltransferases.
ISNAC 2013. The 40th International Symposium on Nucleic Acid Chemistry. Kanagawa: Kanagawa University, 2013. P004-P004.
[ISNAC 2013. The International Symposium on Nucleic Acid Chemistry /40./. 13.11.2013-15.11.2013, Yokohama]
Grant CEP: GA ČR GAP207/11/0108
Grant ostatní: NHMRC(AU) 1030353
Institucionální podpora: RVO:61388963
Klíčová slova: nucleotide analogues * enzyme inhibitors * plasmodium
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0227081 - 4.0385568 - ÚOCHB 2013 NL eng A - Abstrakt
Špaček, Petr - Hocková, Dana - Janeba, Zlatko - Vrbková, Silvie - Edstein, M. - de Jersey, J. - Keough, D. T. - Guddat, L. W.
Acyclic nucleoside bisphosphonates as inhibitors of hypoxanthine-guanine-(xanthine) phosphoribosyltransferases: Potential new anti-malarial compounds.
13th Tetrahedron Symposium. Challenges in Bioorganic and Organic Medicinal Chemistry. Amsterdam: Elsevier, 2012. P2.24-P2.24.
[Tetrahedron Symposium: Challenges in Bioorganic & Organic Medicinal Chemistry /13./. 26.06.2012-29.06.2012, Amsterdam]
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: nucleoside phosphonates * biophosphonates
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0214755 - 5.0379880 - ÚOCHB 2013 CA eng A - Abstrakt
Hocková, Dana - Keough, D. T. - Janeba, Zlatko - Wang, T. - de Jersey, J. - Guddat, L. W.
Novel Type of Acyclic Nucleoside Phosphonates as Inhibitors of 6-Oxopurine Phosphoribosyltransferases: New Potential Antimalarial Chemotherapy Leads.
20th International Round Table on Nucleosides Nucleotides and Nucleic Acids. Montreal: International Society of Nucleosides, Nucleotides and Nucleic Acids, 2012. -.
[International Round Table on Nucleosides Nucleotides and Nucleic Acids /20./. 05.08.2012-09.08.2012, Montreal]
Grant CEP: GA ČR GAP207/11/0108
Grant ostatní: National Health and Medical Research Council(AU) NHMRC 1030353
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: nucleotide analogues * enzyme inhibitors * Plasmodium
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0210740 - 6.0370868 - ÚOCHB 2012 CZ eng A - Abstrakt
Hocková, Dana - Holý, Antonín - Česnek, Michal - Baszczyňski, Ondřej - Tichý, Tomáš - Krečmerová, Marcela - Janeba, Zlatko - Skinner-Adams, T. - Naesens, L. - Keough, D. T. - de Jersey, J. - Guddat, L. W.
Acyclic nucleoside phosphonates as inhibitors of hypoxanthine-guanine-(xanthine) phosphoribosyltransferase: new anti-malarial chemotherapy leads.
46. Pokroky v organické, bioorganické a farmaceutické chemii - "Liblice 2011". Praha: ČSCH, 2011. s. 21-21.
[Pokroky v organické, bioorganické a farmaceutické chemii - "Liblice 2011" /46./. 11.11.2011-13.11.2011, Lázně Bělohrad]
Grant CEP: GA ČR GAP207/11/0108; GA MŠMT 1M0508
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: nucleotide analogues * antiviral activity * antiplasmodial activity * acyclic nucleoside phosphonates
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0204547 - 7.0370017 - ÚOCHB 2012 MX eng A - Abstrakt
Janeba, Zlatko - Hocková, Dana - Holý, Antonín - Česnek, Michal - Baszczyňski, Ondřej - Tichý, Tomáš - Krečmerová, Marcela - Naesens, L. - Skinner-Adams, T. S. - Edstein, M. - Keough, D. T. - de Jersey, J. - Guddat, L. W.
Acyclic Nucleoside Phosphonates as Potential Anti-Malarial Agents.
Zing Conferences 2011. Drug Discovery - Tropical Diseases Conference. Riviera Maya: -, 2011. s. 21-21.
[Zing Conferences 2011. Drug Discovery - Tropical Diseases Conference. 11.12.2011-15.12.2011, Riviera Maya]
Grant CEP: GA ČR GAP207/11/0108; GA MŠMT 1M0508
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: acyclic nucleoside phosphonates * HGXPRT * malaria * Plasmodium
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0203938 - 8.0369215 - ÚOCHB 2012 GR eng A - Abstrakt
Baszczyňski, Ondřej - Jansa, Petr - Hocková, Dana - Janeba, Zlatko - Dračínský, Martin - Holý, Antonín - Keough, D. T. - de Jersey, J. - Guddat, L. W.
Introduction of the ethylphosphonate moiety to secondary hydroxyl as a tool for the synthesis of 3-fluoro-2-(phosphonoethoxy)propyl (FPEP) compounds.
ESOC 2011. 17th European Symposium on Organic Chemistry. Crete: University of Crete, 2011. -.
[ESOC 2011. European Symposium on Organic Chemistry /17./. 10.07.2011-15.07.2011, Crete]
Grant CEP: GA MŠMT 1M0508; GA ČR GAP207/11/0108
Grant ostatní: National Health and Medicinal Research Council(AU) 569703
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: phosphorus * acyclic nucleoside phosphonates * biological activities * fluorine * Michael addition
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0203335 - 9.0367732 - ÚOCHB 2012 US eng A - Abstrakt
Krečmerová, Marcela - Holý, Antonín - Hocková, Dana - Dračínský, Martin - de Jersey, J. - Keough, D. T. - Guddat, L. W.
Synthesis and antimalarial activity of purine 9-[2-hydroxy-3-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogues.
43rd Western Regional Meeting. Pasadena: ACS, 2011. RM WRM17-RM WRM17.
[Western Regional Meeting /43./. 10.11.2011-12.11.2011, Pasadena]
Grant CEP: GA MŠMT 1M0508; GA ČR GAP207/11/0108
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: HGXPRT * plasmodium * acyclic nucleoside phosphonates
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0202298 - 10.0361422 - ÚOCHB 2012 GR eng A - Abstrakt
Hocková, Dana - Holý, Antonín - Andrei, G. - Snoeck, R. - Balzarini, J. - Keough, D. T. - de Jersey, J. - Guddat, L. W.
Acyclic nucleoside phosphonates with branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and biological activity.
ESOC 2011. 17th European Symposium on Organic Chemistry. Crete: University of Crete, 2011.
[ESOC 2011. European Symposium on Organic Chemistry /17./. 10.07.2011-15.07.2011, Crete]
Grant CEP: GA MŠMT 1M0508; GA ČR GAP207/11/0108
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: nucleotide analogues * antiviral activity * antiplasmodial activity
Kód oboru RIV: CC - Organická chemie
Trvalý link: http://hdl.handle.net/11104/0198734