Výsledky vyhledávání
- 1.0491272 - ÚOCHB 2019 CZ eng A - Abstrakt
Hánová, Iva - Brynda, Jiří - Hobizalová, Radka - Alam, N. - Sojka, Daniel - Kopáček, Petr - Marešová, Lucie - Vondrášek, Jiří - Horn, Martin - Schueler-Furman, O. - Mareš, Michael
Novel structural mechanism of allosteric regulation of aspartic peptidases via evolutionary conserved exosite.
Prague Protein Spring Meeting 2018: Proteins at Work. Praha: Ústav organické chemie a biochemie AV ČR, 2018 - (Votrubová, T.; Pergl Šustková, H.; Vondrášek, J.). s. 66. ISBN 978-80-86241-58-6.
[Prague Protein Spring Meeting 2018: Proteins at Work. 03.05.2018-06.05.2018, Praha]
Institucionální podpora: RVO:61388963 ; RVO:60077344
Klíčová slova: aspartic peptidase * IrCD1 * exosite
Obor OECD: Biochemistry and molecular biology
Trvalý link: http://hdl.handle.net/11104/0285576 - 2.0490992 - BC 2019 RIV GB eng J - Článek v odborném periodiku
Assumpção, T.C. - Mizurini, D.M. - Ma, D. - Monteiro, R.Q. - Ahlstedt, S. - Reyes, M. - Kotsyfakis, Michalis - Mather, T. N. - Andersen, J. F. - Lukszo, J. - Ribeiro, J.M.C. - Francischetti, I.M.B.
Ixonnexin from Tick Saliva Promotes Fibrinolysis by Interacting with Plasminogen and Tissue-Type Plasminogen Activator, and Prevents Arterial Thrombosis.
Scientific Reports. Roč. 8, 19 March (2018), č. článku 4806. ISSN 2045-2322. E-ISSN 2045-2322
Grant CEP: GA ČR GAP502/12/2409
Institucionální podpora: RVO:60077344
Klíčová slova: factor pathway inhibitor * heparin-binding exosite * ixodes-scapularis * borrelia-burgdorferi * factor-xa * hematophagous animals * platelet-aggregation * potent inhibitor
Obor OECD: Genetics and heredity (medical genetics to be 3)
Impakt faktor: 4.011, rok: 2018
https://www.nature.com/articles/s41598-018-22780-1
Trvalý link: http://hdl.handle.net/11104/0285092 - 3.0480712 - ÚOCHB 2018 GB eng A - Abstrakt
Hánová, Iva - Brynda, Jiří - Hobizalová, Radka - Alam, N. - Sojka, Daniel - Kopáček, Petr - Marešová, Lucie - Vondrášek, Jiří - Horn, Martin - Schueler-Furman, O. - Mareš, Michael
Novel structural mechanism of allosteric regulation of aspartic peptidases via evolutionary conserved exosite.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 300-301. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institucionální podpora: RVO:61388963 ; RVO:60077344
Klíčová slova: aspartic peptidases * exosite inhibition
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0276419 - 4.0471335 - ÚOCHB 2017 IT eng A - Abstrakt
Hánová, Iva - Brynda, Jiří - Hobizalová, Radka - Alam, N. - Sojka, Daniel - Kopáček, Petr - Horn, Martin - Schueler-Furman, O. - Mareš, Michael
Structural mechanism of regulation of aspartic proteases through a propeptide-binding exosite: a lesson from blood feeding parasites.
Gordon Research Conference on Proteolytic Enzymes & Their Inhibitors. Barga: GRC, 2016.
[Gordon Research Conference on Proteolytic Enzymes & Their Inhibitors. 26.06.2016-01.07.2016, Barga]
Grant CEP: GA ČR GA15-18929S; GA ČR GA13-11043S; GA MŠMT LO1302
Institucionální podpora: RVO:61388963 ; RVO:60077344
Klíčová slova: cathepsin D * exosite * inhibitor
Kód oboru RIV: CE - Biochemie
Trvalý link: http://hdl.handle.net/11104/0268799