Vytisknout
0539170 - ÚMG 2021 RIV GB eng J - Článek v odborném periodiku
Kugler, Michael - Holub, J. - Brynda, Jiří - Pospíšilová, K. - El Anwar, S. - Bavol, D. - Havránek, M. - Král, Vlastimil - Fábry, Milan - Gruner, B. - Řezáčová, Pavlína
The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 35, č. 1 (2020), s. 1800-1810. ISSN 1475-6366. E-ISSN 1475-6374
Institucionální podpora: RVO:68378050
Klíčová slova: tumor hypoxia * medicinal chemistry * drug discovery * binding-sites * inhibition * boron * pharmacophores * opportunities * conjugation * metastasis * Carbonic anhydrase IX * carborane * enzyme inhibitors * structure-activity relationship
Obor OECD: Biochemistry and molecular biology
Impakt faktor: 5.051, rok: 2020
Způsob publikování: Open access
https://www.tandfonline.com/doi/full/10.1080/14756366.2020.1816996
Trvalý link: http://hdl.handle.net/11104/0316870
Kugler, Michael - Holub, J. - Brynda, Jiří - Pospíšilová, K. - El Anwar, S. - Bavol, D. - Havránek, M. - Král, Vlastimil - Fábry, Milan - Gruner, B. - Řezáčová, Pavlína
The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 35, č. 1 (2020), s. 1800-1810. ISSN 1475-6366. E-ISSN 1475-6374
Institucionální podpora: RVO:68378050
Klíčová slova: tumor hypoxia * medicinal chemistry * drug discovery * binding-sites * inhibition * boron * pharmacophores * opportunities * conjugation * metastasis * Carbonic anhydrase IX * carborane * enzyme inhibitors * structure-activity relationship
Obor OECD: Biochemistry and molecular biology
Impakt faktor: 5.051, rok: 2020
Způsob publikování: Open access
https://www.tandfonline.com/doi/full/10.1080/14756366.2020.1816996
Trvalý link: http://hdl.handle.net/11104/0316870