Vytisknout
0492257 - ÚEB 2019 RIV US eng J - Článek v odborném periodiku
Cherukupalli, S. - Chandrasekaran, B. - Kryštof, Vladimír - Aleti, R.R. - Sayyad, N. - Merugu, S.R. - Kushwaha, N.D. - Karpoormath, R.
Synthesis, anticancer evaluation, and molecular docking studies of some novel 4,6-disubstituted pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 (CDK2) inhibitors.
Bioorganic Chemistry. Roč. 79, SEP (2018), s. 46-59. ISSN 0045-2068. E-ISSN 1090-2120
Grant CEP: GA MŠMT(CZ) LO1204; GA ČR GA17-14007S
Institucionální podpora: RVO:61389030
Klíčová slova: cancer-therapy * cell-cycle * cyclin-dependent-kinase-2 * roscovitine * lethality * scaffold * targets * mice * Pyrazolo[3,4-d]pyrimidine * Cyclin dependent kinase inhibitor * Anti-proliferative activity * Molecular docking * glide
Obor OECD: Oncology
Impakt faktor: 3.926, rok: 2018
Trvalý link: http://hdl.handle.net/11104/0285792
Cherukupalli, S. - Chandrasekaran, B. - Kryštof, Vladimír - Aleti, R.R. - Sayyad, N. - Merugu, S.R. - Kushwaha, N.D. - Karpoormath, R.
Synthesis, anticancer evaluation, and molecular docking studies of some novel 4,6-disubstituted pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 (CDK2) inhibitors.
Bioorganic Chemistry. Roč. 79, SEP (2018), s. 46-59. ISSN 0045-2068. E-ISSN 1090-2120
Grant CEP: GA MŠMT(CZ) LO1204; GA ČR GA17-14007S
Institucionální podpora: RVO:61389030
Klíčová slova: cancer-therapy * cell-cycle * cyclin-dependent-kinase-2 * roscovitine * lethality * scaffold * targets * mice * Pyrazolo[3,4-d]pyrimidine * Cyclin dependent kinase inhibitor * Anti-proliferative activity * Molecular docking * glide
Obor OECD: Oncology
Impakt faktor: 3.926, rok: 2018
Trvalý link: http://hdl.handle.net/11104/0285792