Košík

0498922 - BC 2019 RIV US eng J - Článek v odborném periodiku
Doleželová, Eva - Terán, D. - Gahura, Ondřej - Kotrbová, Zuzana - Procházková, Michaela - Keough, D. T. - Špaček, Petr - Hocková, Dana - Guddat, L. - Zíková, Alena
Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
PLoS Neglected Tropical Diseases. Roč. 12, č. 2 (2018), č. článku e0006301. ISSN 1935-2735. E-ISSN 1935-2735
Grant CEP: GA ČR(CZ) GA16-06049S; GA MŠMT LL1205
Institucionální podpora: RVO:60077344 ; RVO:61388963
Klíčová slova: hypoxanthine-guanine phosphoribosyltransferase * acyclic nucleoside phosphonates * human african trypanosomiasis * inducible expression system * purine salvage * plasmodium-falciparum * crystal-structures * xanthine phosphoribosyltransferase * mycobacterium-tuberculosis * antimalarial activity
Obor OECD: Microbiology; Organic chemistry (UOCHB-X)
Impakt faktor: 4.487, rok: 2018
https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0006301
Trvalý link: http://hdl.handle.net/11104/0291797