Košík | Knihovna Akademie věd České republiky

1.

0599204 - FZÚ 2025 RIV NL eng J - Článek v odborném periodiku
Turánek, J. - Kosztyu, P. - Turánek Knötigová, P. - Bartheldyová, E. - Hubatka, F. - Odehnalová, N. - Mikulík, R. - Vaškovicová, N. - Čelechovská, H. - Kratochvílová, Irena - Fekete, Ladislav - Tavares, Marina Rodrigues - Chytil, Petr - Raška, M. - Etrych, Tomáš
Long circulating liposomal platform utilizing hydrophilic polymer-based surface modification: preparation, characterisation, and biological evaluation.
International Journal of Pharmaceutics. Roč. 661, Aug (2024), č. článku 124465. ISSN 0378-5173. E-ISSN 1873-3476
Grant CEP: GA MŠMT(CZ) EH22_008/0004596; GA MZd(CZ) NU21-08-00510
Institucionální podpora: RVO:68378271 ; RVO:61389013
Klíčová slova: stealth liposomes * HPMA copolymer * complement activation * drug delivery system
Obor OECD: Biophysics; Polymer science (UMCH-V)
Impakt faktor: 5.3, rok: 2023 ; AIS: 0.748, rok: 2023
Způsob publikování: Omezený přístup
Web výsledku:
https://doi.org/10.1016/j.ijpharm.2024.124465DOI: https://doi.org/10.1016/j.ijpharm.2024.124465

Liposomes are one of the most important drug delivery vectors, nowadays used in clinics. In general, polyethylene glycol (PEG) is used to ensure the stealth properties of the liposomes. Here, we have employed hydrophilic, biocompatible and highly non-fouling N-(2-hydroxypropyl) methacrylamide (HPMA)-based copolymers containing hydrophobic cholesterol anchors for the surface modification of liposomes, which were prepared by the method of lipid film hydration and extrusion through 100 nm polycarbonate filters. Efficient surface modification of liposomes was confirmed by transmission electron microscopy, atomic force microscopy, and gradient ultracentrifugation. The ability of long-term circulation in the vascular bed was demonstrated in rabbits after i.v. application of fluorescently labelled liposomes. Compared to PEGylated liposomes, HPMA-based copolymer-modified liposomes did not induce specific antibody formation and did not activate murine and human complement.
Trvalý link: https://hdl.handle.net/11104/0356835

2.

0323921 - FGÚ 2009 RIV eng U - Conference, Workshop Arrangement
Ošťádal, Bohuslav - Kolář, František
Mendel symposium II - Genes and the Heart.
[Mendelovo symposium 2 - Geny a srdce.]
[Liblice, 24.09.2008-27.09.2008, (K-WRD 130/101)]
R&D Projects: GA MŠMT(CZ) 1M0510
Institutional research plan: CEZ:AV0Z50110509
Keywords : genes * heart
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

The participants (a total of 130 from 17 countries from all over the world) had a unique opportunity to present and discuss the results of contemporary genetics. A total of 61 lectures were divided in 9 symposia: Angiogenesis, Remodeling, Atherosclerosis, Cardiomyopathies, Hypertension, Conduction system and arrhythmias, Ischemia and protection, Mitochondria and Therapeutic approaches. The integral part of the meeting was the ceremonial presentation of the highest honour of the Academy, the Medals of Merit to outstanding cardiologists from Germany and Great Britain

II. Mendelova symposia (první se konalo v r. 2003 v Brně, v místě geniálního Mendelova objevu) se zúčastnilo 130 vědců ze 17 zemí z celého světa. Bylo předneseno celkem 61 sdělení, která se zabývala aktuálními problémy úlohy genetiky v patogeneze kardiovaskulárních onemocnění
Permanent Link: http://hdl.handle.net/11104/0171750

3.

0184214 - UJF-V 970336 RIV US eng J - Journal Article
Mukhamedzhanov, A. M. - Gagliardi, C. A. - Trache, L. - Tribble, R. E. - Burjan, Václav - Cejpek, Jan - Kroha, Václav - Carstoiu, F.
Asymptotic normalization coefficients for .SUP.10 B - .SUP .9 Be+p.
Physical Review C. Roč. 56, - (1997), s. 1302. ISSN 0556-2813. E-ISSN 2469-9993
R&D Projects: GA AV ČR KSK1048601
Impact factor: 1.975, year: 1997
Permanent Link: http://hdl.handle.net/11104/0080657

4.

0025381 - ÚGN 2006 RIV SIGLE CZ cze J - Článek v odborném periodiku
Klapka, Pavel - Martinát, Stanislav
Geografická analýza vybraných populačních a sídelních charakteristik Krkonoš (1850–2001).
[Geographical Analysis of Selected Population and Settlement Characteristics of the Giant Mountains (1850–2001).]
Opera Corcontica. Roč. 42, č. 42 (2005), s. 139-152. ISSN 0139-925X
Výzkumný záměr: CEZ:AV0Z30860518
Klíčová slova: population * settlement * spatiotemporal comparison * Giant Mountains
Kód oboru RIV: DE - Zemský magnetismus, geodézie, geografie

Příspěvek se zabývá vybranými populačními a sídelními charakteristikami, jejich prostorovou a časovou dynamikou v oblasti Krkonoš. Hledá souvislosti mezi jednotlivými kvantitativními a kvalitativními charakteristika obyvatelstva pohoří. V závěru jsou naznačeny hlavní možnosti dalšího výzkumu v oblasti geografi e obyvatelstva a sídel.

Our contribution deals with selected population and settlement characteristics, their spatial and temporal dynamics in the Giant Mountains (Krkonoše in Czech). It seeks links among particular quantitative and qualitative population characteristics. Main research directions of population and settlement geography are outlined in the conclusion.
Trvalý link: http://hdl.handle.net/11104/0115775

5.

0257362 NL BCA
Optics Communications.
Elsevier. ISSN 0030-4018. E-ISSN 1873-0310

6.

0382640 - BÚ 2014 RIV DE eng J - Článek v odborném periodiku
Vondrák, Jan - Halici, M.G. - Kocakaya, M. - Vondráková, O.
Teloschistaceae (lichenized Ascomycetes) in Turkey. 1. - Some records from Turkey.
Nova Hedwigia. Roč. 94, č. 3-4 (2012), s. 385-396. ISSN 0029-5035. E-ISSN 2363-7188
Institucionální podpora: RVO:67985939
Klíčová slova: arid regions * biodiversity * heterogenous taxa * Caloplaca
Kód oboru RIV: EF - Botanika
Impakt faktor: 0.809, rok: 2012 ; AIS: 0.258, rok: 2012
Web výsledku:
http://botanika.prf.jcu.cz/lichenology/honza/publications/Vondrak_385_396_wm.pdf

DOI: https://doi.org/10.1127/0029-5035/2012/0007

Thirty-seven taxa of Teloschistaceae were identified from samples collected in continental areas of Turkey. Based on previous studies, Caloplaca cerina, C. crenulatella, C. ferrarii, C. haematites and C. variabilis are considered here as heterogeneous taxa. Some poorly characterised lichens were determined with the support of their ITS nrDNA sequences. According to Blast searches, examined samples resembling C. albopruinosa and C. alociza do not group with any known taxa of Caloplaca with endolithic thallus and without anthraquinones.
Trvalý link: http://hdl.handle.net/11104/0212804

7.

0466511 - ÚTIA 2018 RIV CZ eng J - Journal Article
Horváth, Roman - Malega, J.
Financial Stress in the Czech Republic: Measurement and Effects on the Real Economy.
Prague Economic Papers. Roč. 2017, č. 3 (2017), s. 257-268. ISSN 1210-0455. E-ISSN 2336-730X
R&D Projects: GA ČR GA15-10331S
Institutional support: RVO:67985556
Keywords : financial stress indicator * vector autoregression * Czech Republic
OECD category: Finance
Impact factor: 0.409, year: 2017 ; AIS: 0.086, rok: 2017
Result website:
http://library.utia.cas.cz/separaty/2017/E/horvath-0466511.pdf

DOI: https://doi.org/10.18267/j.pep.608

We estimate a financial stress index for the Czech Republic and examine its development during
the 2002–2014 period. We find a marked increase in financial stress at the beginning of the global
financial crisis with a decrease to nearly pre-crisis levels by the end of our study period. Next,
we estimate vector autoregression models of the Czech economy and find that financial stress
has systematic effects on output, prices and interest rates, with the maximum response occurring
approximately one and a half years after the shock. Specifically, an increase in financial stress
is associated with higher unemployment, lower prices and lower interest rates, indicating its
detrimental effects on the real economy.
Permanent Link: http://hdl.handle.net/11104/0270592

8.

0024109 - ÚOCHB 2006 RIV CZ eng C - Conference Paper (international conference)
Šolínová, Veronika - Kašička, Václav - Koval, Dušan - Hlaváček, Jan - Barth, Tomislav
Investigation of structure-mobility relationships and estimation of secondary structure of biopeptides by capillary zone electrophoresis.
[Studium vztahu mezi strukturou a pohyblivostí a určování sekundární struktury biopeptidů kapilární zónovou elektroforézou.]
Biologically Active Peptides. Praha: Ústav organické chemie a biochemie AV ČR, 2005 - (Slaninová, J.), s. 80-83. Collection Symposium Series, 8. ISBN 80-86241-26-2.
[Biologically Active Peptides /9./. Praha (CZ), 20.04.2005-22.04.2005]
R&D Projects: GA ČR(CZ) GA203/03/0716; GA ČR(CZ) GA203/04/0098; GA ČR(CZ) GA203/05/2539
Institutional research plan: CEZ:AV0Z40550506
Keywords : capillary zone electrophoresis * peptides * structure-mobility relationships
Subject RIV: CC - Organic Chemistry

Capillary zone electrophoresis (CZE) has been applied to the analysis, separation and physico-chemical characterization of insect oostatic peptides, enkephalins and dalargin, and their derivatives and fragments.

Kapilární zónová elektroforéza byla využita pro analýzu, separaci a fyzikálně chemickou charakterizaci hmyzích oostatických peptidů, enkefalinů, dalarginu a jejich derivátů a fragmentů.
Permanent Link: http://hdl.handle.net/11104/0114706