Počet záznamů: 1
Antifungal and antioxidant activities of Coleonema album and C. pulchellum against skin diseases
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SYSNO ASEP 0487914 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve SCOPUS Název Antifungal and antioxidant activities of Coleonema album and C. pulchellum against skin diseases Tvůrce(i) Fajinmi, O. O. (ZA)
Grúz, Jiří (UEB-Q) RID, ORCID
Tarkowski, P. (CZ)
Kulkarni, M. G. (ZA)
Finnie, J. F. (ZA)
Van Staden, J. (ZA)Celkový počet autorů 6 Zdroj.dok. Pharmaceutical Biology - ISSN 1388-0209
Roč. 55, č. 1 (2017), s. 1249-1255Poč.str. 7 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova Atopic dermatitis ; Trichophyton mentagrophytes ; Trichophyton rubrum Vědní obor RIV EB - Genetika a molekulární biologie Obor OECD Dermatology and venereal diseases CEP LO1204 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Institucionální podpora UEB-Q - RVO:61389030 EID SCOPUS 85015579251 DOI 10.1080/13880209.2017.1296470 Anotace Context: Coleonema album (Thunb) Bart. & H. L. Wendl (Rutaceae) has been used in the formulation of skincare products, and the Khoisan people rub it on their skin to add luster. Coleonema pulchellum I. Williams has received less attention in the South African traditional medicine. Objective: This study investigates the antifungal and antioxidant activities of C. album and C. pulchellum essential oil (EO) and leaf extracts, and analyzes the chemical components of their EOs. Materials and methods: Antifungal activity of leaf extracts was determined using the microdilution method with griseofulvin and ketoconazole as controls. Antifungal capacity of EO was investigated using the ‘Volatile release plate method’. Trichophyton rubrum (ATCC 28188) and T. mentagrophytes (ATCC 9533) mycelia (0.3cm diameter) were placed on fresh yeast malt agar in Petri dishes with filter paper (impregnated with 20 µL of EO) on the lid for direct exposure to EO volatiles while plates without EO were used as controls. The incubation time was seven days. Antioxidant activities of the leaf extracts were determined. Results: Methanol leaf extract of C. pulchellum inhibited the growth of three fungi tested with MIC values of 195, 391 and 49 µg/mL for Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum gypseum, respectively. Terpenes formed the major components of the EO. The EO from both plants inhibited the growth of T. rubrum in vitro. Discussion and conclusion: This study revealed the therapeutic value of C. pulchellum. Coleonema album and C. pulchellum should be considered as potential plants for skin ointment from natural origin. Pracoviště Ústav experimentální botaniky Kontakt David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Rok sběru 2018 Elektronická adresa http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=MEDLINE&DestLinkType=FullRecord&UT=28262031
Počet záznamů: 1