Poly(glycerol monomethacrylate)-encapsulated upconverting nanoparticles prepared by miniemulsion polymerization: morphology, chemical stability, antifouling properties and toxicity evaluation

Vasylyshyn, Taras; Patsula, Vitalii; Filipová, Marcela; Konefal, Rafal; Horák, Daniel

doi:https://dx.doi.org/10.1039/D3NA00793F

Počet záznamů: 1

Poly(glycerol monomethacrylate)-encapsulated upconverting nanoparticles prepared by miniemulsion polymerization: morphology, chemical stability, antifouling properties and toxicity evaluation

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SYSNO ASEP	0579125
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Poly(glycerol monomethacrylate)-encapsulated upconverting nanoparticles prepared by miniemulsion polymerization: morphology, chemical stability, antifouling properties and toxicity evaluation
Tvůrce(i)	Vasylyshyn, Taras (UMCH-V)_RID Patsula, Vitalii (UMCH-V)_{RID, ORCID} Filipová, Marcela (UMCH-V)_{RID, ORCID} Konefal, Rafal (UMCH-V)_{RID, ORCID} Horák, Daniel (UMCH-V)_{RID, ORCID}
Zdroj.dok.	Nanoscale Advances. - : Royal Society of Chemistry - ISSN 2516-0230 Roč. 5, č. 24 (2023), s. 6979-6989
Poč.str.	11 s.
Jazyk dok.	eng - angličtina
Země vyd.	GB - Velká Británie
Klíč. slova	luminescence ; upconversion ; nanoparticles
Vědní obor RIV	CD - Makromolekulární chemie
Obor OECD	Polymer science
CEP	GA21-04420S GA ČR - Grantová agentura ČR
	LX22NPO5102 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy
Způsob publikování	Open access
Institucionální podpora	UMCH-V - RVO:61389013
UT WOS	001102478900001
EID SCOPUS	85178271635
DOI	10.1039/D3NA00793F
Anotace	In this report, upconverting NaYF4:Yb3+,Er3+ nanoparticles (UCNPs) were synthesized by high-temperature coprecipitation of lanthanide chlorides and encapsulated in poly(glycerol monomethacrylate) (PGMMA). The UCNP surface was first treated with hydrophobic penta(propylene glycol) methacrylate phosphate (SIPO) to improve colloidal stability and enable encapsulation by reversible addition–fragmentation chain transfer miniemulsion polymerization (RAFT) of glycidyl methacrylate (GMA) in water, followed by its hydrolysis. The resulting UCNP-containing PGMMA particles (UCNP@PGMMA), hundreds of nanometers in diameter, were thoroughly characterized by transmission (TEM) and scanning electron microscopy (SEM), dynamic light scattering (DLS), infrared (FTIR) and fluorescence emission spectroscopy, and thermogravimetric analysis (TGA) in terms of particle morphology, size, polydispersity, luminescence, and composition. The morphology, typically raspberry-like, depended on the GMA/UCNP weight ratio. Coating of the UCNPs with hydrophilic PGMMA provided the UCNPs with antifouling properties while enhancing chemical stability and reducing the cytotoxicity of neat UCNPs to a non-toxic level. In addition, it will allow the binding of molecules such as photosensitizers, thus expanding the possibilities for use in various biomedical applications.
Pracoviště	Ústav makromolekulární chemie
Kontakt	Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358
Rok sběru	2024
Elektronická adresa	https://pubs.rsc.org/en/content/articlelanding/2023/NA/D3NA00793F

Počet záznamů: 1