Počet záznamů: 1
Paramagnetic encoding of molecules
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SYSNO ASEP 0558685 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Paramagnetic encoding of molecules Tvůrce(i) Kretschmer, Jan (UOCHB-X)
David, Tomáš (UOCHB-X) RID, ORCID
Dračínský, Martin (UOCHB-X) RID, ORCID
Socha, Ondřej (UOCHB-X) ORCID, RID
Jirák, D. (CZ)
Vít, M. (CZ)
Jurok, R. (CZ)
Kuchař, M. (CZ)
Císařová, I. (CZ)
Polášek, Miloslav (UOCHB-X) ORCIDČíslo článku 3179 Zdroj.dok. Nature Communications. - : Nature Publishing Group
Roč. 13, č. 1 (2022)Poč.str. 12 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova solid-phase synthesis ; contrast agents ; information Obor OECD Organic chemistry CEP GJ17-22834Y GA ČR - Grantová agentura ČR Způsob publikování Open access Institucionální podpora UOCHB-X - RVO:61388963 UT WOS 000809119000011 EID SCOPUS 85131622648 DOI 10.1038/s41467-022-30811-9 Anotace Contactless digital tags are increasingly penetrating into many areas of human activities. Digitalization of our environment requires an ever growing number of objects to be identified and tracked with machine-readable labels. Molecules offer immense potential to serve for this purpose, but our ability to write, read, and communicate molecular code with current technology remains limited. Here we show that magnetic patterns can be synthetically encoded into stable molecular scaffolds with paramagnetic lanthanide ions to write digital code into molecules and their mixtures. Owing to the directional character of magnetic susceptibility tensors, each sequence of lanthanides built into one molecule produces a unique magnetic outcome. Multiplexing of the encoded molecules provides a high number of codes that grows double-exponentially with the number of available paramagnetic ions. The codes are readable by nuclear magnetic resonance in the radiofrequency (RF) spectrum, analogously to the macroscopic technology of RF identification. A prototype molecular system capable of 16-bit (65,535 codes) encoding is presented. Future optimized systems can conceivably provide 64-bit (~10^19 codes) or higher encoding to cover the labelling needs in drug discovery, anti-counterfeiting and other areas. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Rok sběru 2023 Elektronická adresa https://doi.org/10.1038/s41467-022-30811-9
Počet záznamů: 1