Počet záznamů: 1
Antibacterial Nanoparticles with Natural Photosensitizers Extracted from Spinach Leaves
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SYSNO ASEP 0551259 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Antibacterial Nanoparticles with Natural Photosensitizers Extracted from Spinach Leaves Tvůrce(i) Ludačka, P. (CZ)
Kubát, Pavel (UFCH-W) RID, ORCID, SAI
Bosáková, Z. (CZ)
Mosinger, J. (CZ)Zdroj.dok. ACS Omega. - : American Chemical Society - ISSN 2470-1343
Roč. 7, č. 1 (2022), s. 1505-1513Poč.str. 9 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova singlet oxygen ; photodynamic therapy ; molecular-oxygen ; chlorophyll ; carotenoids ; phthalocyanines ; polystyrene ; derivatives ; yields ; state Vědní obor RIV CF - Fyzikální chemie a teoretická chemie Obor OECD Physical chemistry CEP GA19-09721S GA ČR - Grantová agentura ČR Způsob publikování Open access Institucionální podpora UFCH-W - RVO:61388955 UT WOS 000734279500001 EID SCOPUS 85122036780 DOI 10.1021/acsomega.1c06229 Anotace We prepared antibacterial polystyrene nanoparticles (NPs) with natural photosensitizers from chlorophyll (Chl) extract via a simple nanoprecipitation method using the same solvent for dissolution of the polystyrene matrix and extraction of Chls from spinach leaves. A high photo-oxidation and antibacterial effect was demonstrated on Escherichia coli and was based on the photo generation of singlet oxygen O-2((1)Delta(g)), which was directly monitored by NIR luminescence measurements and indirectly verified using a chemical trap. The photoactivity of NPs was triggered by visible light, with enhanced red absorption by Chls. To reduce the quenching effect of carotenoids (beta-carotene, lutein, etc.) in the Chl extract, diluted and/or preirradiated samples, in which the photo-oxidized carotenoids lose their quenching effect, were used for preparation of the NPs. For enhanced photo-oxidation and antibacterial effects, a sulfonated polystyrene matrix was used for preparation of a stable dispersion of sulfonated NPs, with the quenching effect of carotenoids being suppressed. Pracoviště Ústav fyzikální chemie J.Heyrovského Kontakt Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196 Rok sběru 2023 Elektronická adresa http://hdl.handle.net/11104/0326699http://hdl.handle.net/11104/0326699
Počet záznamů: 1