Počet záznamů: 1
Incidence of congenital anomalies in children born after assisted reproduction in the Czech Republic
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SYSNO ASEP 0547262 Druh ASEP A - Abstrakt Zařazení RIV Záznam nebyl označen do RIV Zařazení RIV Není vybrán druh dokumentu Název Incidence of congenital anomalies in children born after assisted reproduction in the Czech Republic Tvůrce(i) Šípek, A. (CZ)
Gregor, V. (CZ)
Klaschka, Jan (UIVT-O) RID, SAI, ORCID
Malý, Marek (UIVT-O) RID, SAI
Šípek jr., A. (CZ)Zdroj.dok. International Journal of Epidemiology - ISSN 0300-5771
Roč. 50, Suppl. 1 (2021), s. 219-220Poč.str. 2 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Institucionální podpora UIVT-O - RVO:67985807 UT WOS 000695815900597 DOI 10.1093/ije/dyab168.619 Anotace Background: The number of children conceived by assisted reproduction techniques (ART) is increasing in the Czech Republic. However, several studies reported increased incidence of congenital anomalies in ART conceived children. The main goal of this study was to evaluate this theoretical risk using population-based data from Czech medial registries. Methods: The retrospective epidemiological analysis was performed using data from the National Registry of Congenital Anomalies and National Registry of Newborns, run by the Institute of Health Information and Statistics of the Czech Republic. All diagnoses of congenital anomalies (Q00-Q99) were included. We compared the incidences of congenital anomalies in naturally conceived children and ART conceived children born in the Czech Republic during 5 years period (2013-2017). Statistical analysis was performed by Fisher's exact test. Results: During the selected period there were 547 675 children born in the Czech Republic (531 064 were naturally conceived children and 16 611 were ART conceived children). The incidence of congenital anomalies was 3.90% in naturally conceived children group and 4.35% in ART conceived children. This difference is statistically significant (p = 0.003). Conclusions: In our population-based study, we confirmed a significantly higher general incidence of congenital anomalies in ART conceived children. Key messages: The general incidence of congenital anomalies in ART conceived children is higher (compared to the incidence of congenital anomalies in naturally conceived children). Possible causes of this phenomenon shall be further analysed. Pracoviště Ústav informatiky Kontakt Tereza Šírová, sirova@cs.cas.cz, Tel.: 266 053 800 Rok sběru 2022
Počet záznamů: 1