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The use of a battery of examination methods for detection of cervical metastases in squamous cell carcinoma of the oral cavity
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SYSNO ASEP 0545132 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název The use of a battery of examination methods for detection of cervical metastases in squamous cell carcinoma of the oral cavity Tvůrce(i) Štembírek, Jan (UZFG-Y) ORCID
Čermáková, Z. (CZ)
Kulnig, M. (CZ)
Hurník, P. (CZ)
Cvek, J. (CZ)
Resová, K. (CZ)
Jonszta, T. (CZ)
Litschmanová, M. (CZ)
Stránský, J. (CZ)Zdroj.dok. Biomedical Papers. - : Univerzita Palackého v Olomouci - ISSN 1213-8118
Roč. 165, č. 2 (2021), s. 224-228Poč.str. 5 s. Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. CZ - Česká republika Klíč. slova squamous cell carcinoma ; oral cavity ; cervical metastasis Vědní obor RIV EB - Genetika a molekulární biologie Obor OECD Oncology CEP NV19-08-00383 GA MZd - Ministerstvo zdravotnictví Způsob publikování Open access Institucionální podpora UZFG-Y - RVO:67985904 UT WOS 000660244900019 EID SCOPUS 85108896133 DOI 10.5507/bp.2020.026 Anotace Introduction. In patients with squamous cell carcinoma of the orofacial area, the presence of cervical metastases represents a single most significant prognostic factor. This fact underlines the importance of thorough examination of the cervical lymph nodes for potential tumor involvement. To verify this, the most common investigative methods are physical examination (PE), sonography (US) and computed tomography (CT), which have also been used to assess the stage of the disease in the patients in our research.
Objective. To evaluate the performance of individual methods (physical examination, sonography, computed tomography) and combinations.
Method. Patients with squamous cell carcinoma of the oral cavity, who had undergone physical, US and CT examinations at our department followed by radical neck dissection were included in this retrospective study. A total of 57 patients were included.
Results. The sensitivity of PE, US and CT were 38%, 69% and 61%, respectively, however CT+US combination yielded 83% sensitivity and combination of all these methods 86% sensitivity. The number of false positives was however relatively high with specificity of the 3-way combination at 65%.
Conclusion. A combination of our three widely available inexpensive methods detected 86% of metastases in cervical nodes. The large number of false positives however indicates that the method should rather be used for screening in selecting patients who need additional and more expensive imaging than for diagnosing cervical metastases. Also, as 14% of cervical metastases pass undetected using our method, we would recommend an additional examination at least by US+PE several weeks to a few months after the initial examination.Pracoviště Ústav živočišné fyziologie a genetiky Kontakt Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Rok sběru 2022 Elektronická adresa https://biomed.papers.upol.cz/pdfs/bio/2021/02/19.pdf
Počet záznamů: 1