Počet záznamů: 1  

Enhanced visible light-triggered antibacterial activity of carbon quantum dots/polyurethane nanocomposites by gamma rays induced pre-treatment

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    SYSNO ASEP0542909
    Druh ASEPJ - Článek v odborném periodiku
    Zařazení RIVJ - Článek v odborném periodiku
    Poddruh JČlánek ve WOS
    NázevEnhanced visible light-triggered antibacterial activity of carbon quantum dots/polyurethane nanocomposites by gamma rays induced pre-treatment
    Tvůrce(i) Budimir, M. (RS)
    Marković, Z. (RS)
    Vajďák, J. (CZ)
    Jovanović, S. (RS)
    Kubát, Pavel (UFCH-W) RID, ORCID, SAI
    Humpolíček, P. (CZ)
    Mičušik, M. (SK)
    Danko, M. (SK)
    Barras, A. (FR)
    Milivojević, D. D. (RS)
    Špitalsky, Z. (SK)
    Boukherroub, R. (FR)
    Marković, B. T. (RS)
    Číslo článku109499
    Zdroj.dok.Radiation Physics and Chemistry. - : Elsevier - ISSN 0969-806X
    Roč. 185, AUG 2021 (2021)
    Poč.str.13 s.
    Jazyk dok.eng - angličtina
    Země vyd.GB - Velká Británie
    Klíč. slovaAntibacterial photodynamic therapy ; Carbon quantum dots ; Gamma-irradiation ; Polymer-matrix composite ; Reactive oxygen species
    Vědní obor RIVCF - Fyzikální chemie a teoretická chemie
    Obor OECDPhysical chemistry
    Způsob publikováníOmezený přístup
    Institucionální podporaUFCH-W - RVO:61388955
    UT WOS000655300100004
    EID SCOPUS85105360471
    DOI10.1016/j.radphyschem.2021.109499
    AnotacePersistent microbial contamination of medical implant surfaces is becoming a serious threat to public health. This is principally due to antibiotic-resistant bacterial strains and the formation of bacterial biofilms. The development of novel antibacterial materials that will effectively fight both Gram-positive and Gram-negative bacteria and prevent biofilm formation represents a big challenge for researchers in the last few decades. In the present work, we report an antibacterial hydrophobic carbon quantum dots/polyurethane nanocomposite (hCQD-PU), with enhanced antibacterial properties induced by pre-treatment with gamma-irradiation. Hydrophobic quantum dots (hCQDs), which are capable of generating reactive oxygen species (ROS) upon irradiation with low-power blue light (470 nm), have been integrated into the polyurethane (PU) polymer matrix to form a photoactive nanocomposite. To modify its physical and chemical properties and improve its antibacterial efficacy, various doses of gamma irradiation (1, 10, and 200 kGy) in the air environment were applied to the formed nanocomposite. Gamma-irradiation pre-treatment significantly influenced the rise in ROS production, therefore, the prooxidative activity under the blue-light illumination of hCQD-PU was also significantly improved. The best antibacterial activity was demonstrated by the hCQD-PU nanocomposite irradiated with a dose of 200 kGy, with the complete eradication of Gram-positive Staphylococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli) bacteria after 15 min of exposure to the blue lamp.
    PracovištěÚstav fyzikální chemie J.Heyrovského
    KontaktMichaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196
    Rok sběru2022
    Elektronická adresahttp://hdl.handle.net/11104/0320242
Počet záznamů: 1