Počet záznamů: 1
Comparison of macro-, micro- and nanomechanical properties of clinically-relevant UHMWPE formulations
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SYSNO ASEP 0542837 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Comparison of macro-, micro- and nanomechanical properties of clinically-relevant UHMWPE formulations Tvůrce(i) Šlouf, Miroslav (UMCH-V) RID, ORCID
Arevalo, S. (US)
Vlková, Helena (UMCH-V)
Gajdošová, Veronika (UMCH-V) RID, ORCID
Králík, V. (CZ)
Pruitt, L. (US)Číslo článku 104205 Zdroj.dok. Journal of the Mechanical Behavior of Biomedical Materials. - : Elsevier - ISSN 1751-6161
Roč. 120, August (2021)Poč.str. 16 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova UHMWPE ; macro- ; micro- and nanomechanical properties Vědní obor RIV CD - Makromolekulární chemie Obor OECD Polymer science CEP NV15-31269A GA MZd - Ministerstvo zdravotnictví LO1507 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Způsob publikování Omezený přístup Institucionální podpora UMCH-V - RVO:61389013 UT WOS 000663145300006 EID SCOPUS 85107038038 DOI 10.1016/j.jmbbm.2020.104205 Anotace We characterized a set of eleven clinically relevant formulations of UHMWPE for total joint replacements. Although their molecular and supermolecular structure were quite similar as evidenced by IR, DSC and SAXS measurements, there were slight differences in their crystallinity (DSC crystallinity ranging from 52 to 61%), which were connected with processing conditions, such as the total radiation dose, thermal treatment and/or addition of biocompatible stabilizers. Mechanical properties were assessed at all length scales, using macroscale compression testing, non-instrumented and instrumented microindentation hardness testing (at loading forces ~500 mN), and nanoindentation hardness testing measured at both higher and lower loading (~4 mN and ~0.6 mN, respectively). In agreement with theoretical predictions, we found linear correlations between UHMWPE crystallinity and its stiffness-related properties (elastic moduli, yield stress, and hardness) at all length scales (macro-, micro- and nanoscale). Detailed statistical evaluation of our dataset showed that the accuracy and precision of the applied methods decreased in the following order: non-instrumented microindentation ≥ instrumented microindentation ≥ macromechanical properties ≥ nanoindentation measured at higher loading forces ≫ nanoindentation measured at lower loading forces. The results confirm that microindentation and nanoindentation at sufficiently high loading forces are reliable methods, suitable for UHMWPE characterization. Pracoviště Ústav makromolekulární chemie Kontakt Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Rok sběru 2022 Elektronická adresa https://www.sciencedirect.com/science/article/pii/S1751616120307475?via%3Dihub
Počet záznamů: 1