Počet záznamů: 1
Critical Analysis of Non-Thermal Plasma-Driven Modulation of Immune Cells from Clinical Perspective
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SYSNO ASEP 0540034 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Critical Analysis of Non-Thermal Plasma-Driven Modulation of Immune Cells from Clinical Perspective Tvůrce(i) Smolková, B. (CZ)
Frtus, A. (CZ)
Uzhytchak, M. (CZ)
Lunova, M. (CZ)
Kubinová, Šárka (UEM-P) RID, ORCID
Dejneka, A. (CZ)
Lunov, O. (CZ)Číslo článku 6226 Zdroj.dok. International Journal of Molecular Sciences. - : MDPI
Roč. 21, č. 17 (2020)Poč.str. 24 s. Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova non-thermal plasma ; cytotoxicity ; cell signaling Vědní obor RIV BO - Biofyzika Obor OECD Biophysics CEP FV10081 GA MPO - Ministerstvo průmyslu a obchodu Způsob publikování Open access Institucionální podpora UEM-P - RVO:68378041 UT WOS 000569583400001 EID SCOPUS 85090179717 DOI 10.3390/ijms21176226 Anotace The emerged field of non-thermal plasma (NTP) shows great potential in the alteration of cell redox status, which can be utilized as a promising therapeutic implication. In recent years, the NTP field considerably progresses in the modulation of immune cell function leading to promising in vivo results. In fact, understanding the underlying cellular mechanisms triggered by NTP remains incomplete. In order to boost the field closer to real-life clinical applications, there is a need for a critical overview of the current state-of-the-art. In this review, we conduct a critical analysis of the NTP-triggered modulation of immune cells. Importantly, we analyze pitfalls in the field and identify persisting challenges. We show that the identification of misconceptions opens a door to the development of a research strategy to overcome these limitations. Finally, we propose the idea that solving problems highlighted in this review will accelerate the clinical translation of NTP-based treatments. Pracoviště Ústav experimentální medicíny Kontakt Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Rok sběru 2021 Elektronická adresa https://www.mdpi.com/1422-0067/21/17/6226
Počet záznamů: 1