Počet záznamů: 1
Effect of Polycyclic Aromatic Hydrocarbons Exposure on Cognitive Development in 5 Years Old Children
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SYSNO ASEP 0539320 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Effect of Polycyclic Aromatic Hydrocarbons Exposure on Cognitive Development in 5 Years Old Children Tvůrce(i) Blažková, B. (CZ)
Pastorková, Anna (UEM-P) RID
Solanský, I. (CZ)
Veleminský Jr., M. (CZ)
Veleminský, M. (CZ)
Urbancová, K. (CZ)
Vondrašková, V. (CZ)
Hajslová, J. (CZ)
Pulkrabová, J. (CZ)
Šrám, Radim (UEM-P) RIDČíslo článku 619 Zdroj.dok. Brain Sciences. - : MDPI
Roč. 10, č. 9 (2020)Poč.str. 11 s. Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova polycyclic aromatic hydrocarbons ; OH-PAH metabolites in urine ; psychological tests Vědní obor RIV DN - Vliv životního prostředí na zdraví Obor OECD Public and environmental health CEP EF16_019/0000798 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Způsob publikování Open access Institucionální podpora UEM-P - RVO:68378041 UT WOS 000581698700001 EID SCOPUS 85090350933 DOI 10.3390/brainsci10090619 Anotace Objectives: To analyze the impact of polycyclic aromatic hydrocarbons (PAHs) in ambient air at the time of delivery and five years of age on cognitive development in five year old children. Materials and Methods: Two cohorts of children born in the years 2013 and 2014 from Karvina (Northern Moravia, n = 70) and Ceske Budejovice (Southern Bohemia, n = 99) were studied at the age of five years for their cognitive development related to the exposure to PAHs, determined in the ambient air as the concentration of benzo[a]pyrene (B[a]P) and OH-PAH (hydroxy-PAH) metabolites in urine of the newborns at the time of delivery. As psychological tests, the Bender Visual Motor Gestalt Test (BG test) and the Raven Colored Progressive Matrices (RCPM test) were used. Results: Concentrations of B[a]P in the third trimester of mother's pregnancies were 6.1 +/- 4.53 ng/m(3) in Karvina, and 1.19 +/- 1.28 ng/m(3) (p < 0.001) in Ceske Budejovice. Neither the outcome of the RCPM test nor the BG test differed between children in Karvina vs. Ceske Budejovice, or boys vs. girls. Cognitive development in five year old children was affected by the higher exposure to PM2.5 during the third trimester in girls in Karvina. Conclusions: We did not observe any significant effect of prenatal PAH exposure on psychological cognitive tests in five year old children. Pracoviště Ústav experimentální medicíny Kontakt Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Rok sběru 2021 Elektronická adresa https://www.mdpi.com/2076-3425/10/9/619
Počet záznamů: 1