Počet záznamů: 1
NeuroPsychopharmacotherapy
- 1.
SYSNO ASEP 0535914 Druh ASEP M - Kapitola v monografii Zařazení RIV Záznam nebyl označen do RIV Název Anti-convulsant agents: Cortisone and Adrenocorticotropic Hormone (ACTH) Tvůrce(i) Kubová, Hana (FGU-C) RID, ORCID
Jiruška, Přemysl (FGU-C) RID, ORCID, SAI
Komárek, V. (CZ)Zdroj.dok. NeuroPsychopharmacotherapy. - Cham : Springer, 2020 / Riederer Peter ; Laux Gerd ; Nagatsu Toshiharu - ISBN 978-3-319-56015-1 Rozsah stran s. 1-15 Poč.str. 15 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova infantile spasms ; adrenocorticotropic hormone ; corticoids Vědní obor RIV FH - Neurologie, neurochirurgie, neurovědy Obor OECD Neurosciences (including psychophysiology Institucionální podpora FGU-C - RVO:67985823 DOI 10.1007/978-3-319-56015-1_305-1 Anotace Adrenocorticotropic hormone (ACTH) and corticoids represent the first-line treatment of the infantile spasms-West syndrome. The exact cellular and network mechanisms behind the anti-epileptic effect of ACTH and corticoids are not known. In the brain, these substances display multiple effects ranging from controlling inflammation, brain maturation, and cellular proliferation to the modulation of several neurotransmitter systems. ACTH and corticoids display multiple systemic effects on the body mainly on glucose metabolism and immune system. Therefore, their administration is associated with increased risk of severe side effects. ACTH and steroids display nearly identical efficacy in controlling infantile spasms. The popularity of corticoids in the treatment of infantile spasms is increasing due to their advantages which include oral route of administration, lower risk of side effects, and low cost. Apart from infantile spasms, corticoids are also used in the treatment of other epileptic syndromes in childhood including Lennox-Gastaut syndrome, Landau-Kleffner syndrome, or electrical status epilepticus in sleep syndrome. Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2025 Elektronická adresa https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-56015-1_305-1
Počet záznamů: 1