Počet záznamů: 1  

Current and Future Aspects of Nanomedicine

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    SYSNO ASEP0534382
    Druh ASEPM - Kapitola v monografii
    Zařazení RIVC - Kapitola v knize
    NázevNanofibrous Scaffolds for Skin Tissue Engineering and Wound Healing Based on Nature-Derived Polymers
    Tvůrce(i) Bačáková, Lucie (FGU-C) RID, ORCID
    Pajorová, Julia (FGU-C)
    Zikmundová, Markéta (FGU-C)
    Filová, Elena (FGU-C) RID, ORCID
    Mikeš, P. (CZ)
    Jenčová, V. (CZ)
    Kuželová Košťáková, E. (CZ)
    Sinica, A. (CZ)
    Zdroj.dok.Current and Future Aspects of Nanomedicine. - London : IntechOpen, 2020 / Khalil Islam - ISBN 978-1-78985-870-9
    Rozsah strans. 1-30
    Poč.str.30 s.
    Poč.str.knihy142
    Forma vydáníOnline - E
    Jazyk dok.eng - angličtina
    Země vyd.GB - Velká Británie
    Klíč. slovaskin replacements ; wound dressings ; nanofibers ; electrospinning ; dermis ; epidermis ; keratinocytes ; fibroblasts ; stem cells ; vascularization ; cell delivery ; drug delivery ; regenerative medicine
    Vědní obor RIVEI - Biotechnologie a bionika
    Obor OECDTechnologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)
    CEPGA17-02448S GA ČR - Grantová agentura ČR
    GA17-00885S GA ČR - Grantová agentura ČR
    Institucionální podporaFGU-C - RVO:67985823
    DOI10.5772/intechopen.88602
    AnotaceNanofibrous scaffolds belong to the most suitable materials for tissue engineering, because they mimic the fibrous component of the natural extracellular matrix. This chapter is focused on the application of nanofibers in skin tissue engineering and wound healing, because the skin is the largest and vitally important organ in the human body. Nanofibrous meshes can serve as substrates for adhesion, growth and differentiation of skin and stem cells, and also as an antimicrobial and moisture-retaining barrier. These meshes have been prepared from a wide range of synthetic and nature-derived polymers. This chapter is focused on the use of nature-derived polymers. These polymers have good or limited degradability in the human tissues, which depends on their origin and on the presence of appropriate enzymes in the human tissues. Non-degradable and less-degradable polymers are usually produced in bacteria, fungi, algae, plants or insects, and include, for example, cellulose, dextran, pullulan, alginate, pectin and silk fibroin. Well-degradable polymers are usually components of the extracellular matrix in the human body or at least in other vertebrates, and include collagen, elastin, keratin and hyaluronic acid, although some polymers produced by non-vertebrate organisms, such as chitosan or poly(3-hydroxybutyrate-co-3-hydroxyvalerate), are also degradable in the human body.
    PracovištěFyziologický ústav
    KontaktLucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
    Rok sběru2021
    Elektronická adresahttps://www.intechopen.com/online-first/nanofibrous-scaffolds-for-skin-tissue-engineering-and-wound-healing-based-on-nature-derived-polymers
Počet záznamů: 1  

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