Počet záznamů: 1
Typicality of Functional Connectivity Robustly Captures Motion Artifacts in rs‐fMRI across Datasets, Atlases, and Preprocessing Pipelines
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SYSNO ASEP 0532231 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Typicality of Functional Connectivity Robustly Captures Motion Artifacts in rs‐fMRI across Datasets, Atlases, and Preprocessing Pipelines Tvůrce(i) Kopal, Jakub (UIVT-O) RID, ORCID, SAI
Pidnebesna, Anna (UIVT-O) SAI, ORCID, RID
Tomeček, D. (CZ)
Tintěra, J. (CZ)
Hlinka, Jaroslav (UIVT-O) RID, SAI, ORCIDCelkový počet autorů 5 Zdroj.dok. Human Brain Mapping. - : Wiley - ISSN 1065-9471
Roč. 41, č. 18 (2020), s. 5325-5340Poč.str. 16 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova atlas ; functional connectivity ; motion ; quality ; rs‐fMRI Vědní obor RIV IN - Informatika Obor OECD Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8) CEP GA17-01251S GA ČR - Grantová agentura ČR Způsob publikování Open access Institucionální podpora UIVT-O - RVO:67985807 UT WOS 000565321100001 EID SCOPUS 85090109459 DOI 10.1002/hbm.25195 Anotace Functional connectivity analysis of resting‐state fMRI data has recently become one of the most common approaches to characterizing individual brain function. It has been widely suggested that the functional connectivity matrix is a useful approximate representation of the brain's connectivity, potentially providing behaviorally or clinically relevant markers. However, functional connectivity estimates are known to be detrimentally affected by various artifacts, including those due to in‐scanner head motion. Moreover, as individual functional connections generally covary only very weakly with head motion estimates, motion influence is difficult to quantify robustly, and prone to be neglected in practice. Although the use of individual estimates of head motion, or group‐level correlation of motion and functional connectivity has been suggested, a sufficiently sensitive measure of individual functional connectivity quality has not yet been established. We propose a new intuitive summary index, Typicality of Functional Connectivity, to capture deviations from standard brain functional connectivity patterns. In a resting‐state fMRI dataset of 245 healthy subjects, this measure was significantly correlated with individual head motion metrics. The results were further robustly reproduced across atlas granularity, preprocessing options, and other datasets, including 1,081 subjects from the Human Connectome Project. In principle, Typicality of Functional Connectivity should be sensitive also to other types of artifacts, processing errors, and possibly also brain pathology, allowing extensive use in data quality screening and quantification in functional connectivity studies as well as methodological investigations. Pracoviště Ústav informatiky Kontakt Tereza Šírová, sirova@cs.cas.cz, Tel.: 266 053 800 Rok sběru 2021 Elektronická adresa http://hdl.handle.net/11104/0310801
Počet záznamů: 1